Claus Henrik Nielsen

Claus Henrik Nielsen

Professor

ORCID: 0000-0001-7543-9016

Publication year:
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1 - 158 out of 158Page size: 500
  1. 2024
  2. E-pub ahead of print

    Suitability of machine learning models for prediction of clinically defined Stage III/IV periodontitis from questionnaires and demographic data in Danish cohorts

    Enevold, Christian, Nielsen, Claus Henrik, Christensen, Lisa Bøge, Kongstad, Johanne, Fiehn, Nils-Erik, Hansen, Peter Riis, Holmstrup, Palle, Havemose-Poulsen, A. & Damgaard, Christian, 2024, (E-pub ahead of print) In: Journal of Clinical Periodontology. 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    B-cell cytokine responses to Porphyromonas gingivalis in patients with periodontitis and healthy controls

    Danielsen, Anne Katrine, Damgaard, Christian, Massarenti, Laura, Jensen, Peter Østrup, Hansen, Peter Riis, Holmstrup, Palle & Nielsen, Claus Henrik, 2023, In: Journal of Periodontology. 94, 8, p. 997-1007 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Blood Cell Biomarkers of Inflammation and Cytokine Levels as Predictors of Response to Biologics in Patients with Psoriasis

    Andersen, C. S. B., Kvist-Hansen, A., Siewertsen, M., Enevold, C., Hansen, Peter Riis, Knudsen, Diljit Kaur, Zachariae, Claus, Nielsen, Claus Henrik, Loft, N. & Skov, Lone, 2023, In: International Journal of Molecular Sciences. 24, 7, 15 p., 6111.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cerebral abscesses with odontogenic origin: a population-based cohort study

    Jespersen, Frederik Viktor Bang, Hansen, S. U., Jensen, Simon Storgård, Omland, L. H., Helweg-Larsen, J., Bjarnsholt, Thomas, Nielsen, Claus Henrik, Ziebell, M., Bodilsen, J. & Markvart, Merete, 2023, In: Clinical Oral Investigations. 27, 7, p. 3639-364

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Characterization of circulating extracellular traps and immune responses to citrullinated LL37 in psoriasis

    Monreal, M. T. M., Kvist-Hansen, A., Massarenti, Laura, Steffensen, R., Loft, N., Hansen, Peter Riis, Ødum, Niels, Skov, Lone & Nielsen, Claus Henrik, 2023, In: Frontiers in Immunology. 14, 10 p., 1247592.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Characterization of patients with odontogenic necrotizing soft tissue infections in the head and neck area: A retrospective analysis

    Hansen, S. U., Jespersen, Frederik Viktor Bang, Markvart, Merete, Hyldegaard, Ole, Plaschke, Christina Caroline, Bjarnsholt, Thomas, Nielsen, Claus Henrik & Jensen, Simon Storgård, 2023, In: Acta Odontologica Scandinavica. 82, 1, p. 40-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Citrullination of myelin basic protein induces a Th17-cell response in healthy individuals and enhances the presentation of MBP85-99 in patients with multiple sclerosis

    Martín Monreal, M. T., Hansen, B. E., Iversen, P. F., Enevold, Christian, Ødum, Niels, Sellebjerg, Finn Thorup, Højrup, P., von Essen, Marina Rode & Nielsen, Claus Henrik, 2023, In: Journal of Autoimmunity. 139, 103092.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Interferon alpha-2 treatment reduces circulating neutrophil extracellular trap levels in myeloproliferative neoplasms

    Massarenti, Laura, Knudsen, T. A., Enevold, Christian, Skov, V., Kjær, L., Larsen, M. K., Larsen, T. S., Hansen, D. L., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, 2023, In: British Journal of Haematology. 202, 2, p. 318-327 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Markers of neutrophil chemotaxis for identification of blood stream infections in children with acute lymphoblastic leukemia undergoing induction treatment

    Weischendorff, S., De Pietri, S., Rathe, M., Frandsen, T. L., Hasle, H., Nielsen, Claus Henrik, Moser, Claus Ernst & Muller, Klaus, 2023, In: European Journal of Haematology. 110, 6, p. 762-771

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Sjögren's syndrome: novel insights from proteomics and miRNA expression analysis

    Kamounah, Sarah, Sembler-Møller, Maria Lynn, Nielsen, Claus Henrik & Pedersen, Anne Marie Lynge, 2023, In: Frontiers in Immunology. 14, 21 p., 1183195.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Treated periodontitis and recurrent events after first-time myocardial infarction: A Danish nationwide cohort study

    Wagner, A. K., D'Souza, M., Bang, C. N., Holmstrup, Palle, Blanche, Paul Frédéric, Fiehn, Nils-Erik, Gislason, Gunnar Hilmar, Torp-Pedersen, Christian, Damgaard, Christian, Nielsen, Claus Henrik & Hansen, Peter Riis, 2023, In: Journal of Clinical Periodontology. 50, 10, p. 1305-1314 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2022
  15. Published

    Complement component 3 and its activation split-products in saliva associate with periodontitis

    Damgaard, Christian, Massarenti, Laura, Danielsen, Anne Katrine, Graversen, J. H., Holmstrup, Palle, Nielsen, Claus Henrik & Palarasah, Y., 2022, In: Journal of Periodontology. 93, 9, p. 1294-1301 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Influence of Insulin Receptor Single Nucleotide Polymorphisms on Glycaemic Control and Formation of Anti-Insulin Antibodies in Diabetes Mellitus

    Massarenti, Laura, Aniol-Nielsen, C., Enevold, C., Toft-Hansen, H. & Nielsen, Claus Henrik, 2022, In: International Journal of Molecular Sciences. 23, 12, 13 p., 6481.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Peptidylarginine Deiminase 2 Gene Polymorphisms in Subjects with Periodontitis Predispose to Rheumatoid Arthritis

    Massarenti, Laura, Enevold, C., Damgaard, D., Hansen, Peter Riis, Frisch, M., Ødum, Niels, Jacobsen, Søren & Nielsen, Claus Henrik, 2022, In: International Journal of Molecular Sciences. 23, 17, 10 p., 9536.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Severe weight loss in a hypothyroid patient as an acute presentation of autoimmune polyglandular syndrome type II

    Silajdzija, E., Bliddal, S., Borgwardt, L., Rossing, M., Jarløv, A., Nielsen, Claus Henrik & Feldt-Rasmussen, Ulla, 2022, In: Hormones. 21, 2, p. 317-322

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Thymic stromal lymphopoietin levels after allogeneic hematopoietic stem cell transplantation

    Møller, D. L., Kielsen, K., Nielsen, Claus Henrik, Sengeløv, Henrik, Pedersen, Anders Elm, Ryder, L. P. & Muller, Klaus, 2022, In: Immunopharmacology and Immunotoxicology. 44, 6, p. 1004-1012 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2021
  21. Published

    PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking

    Massarenti, Laura, Enevold, C., Damgaard, D., Ødum, Niels, Garred, Peter, Frisch, M., Shelef, M. A., Jacobsen, Søren & Nielsen, Claus Henrik, 2021, In: Frontiers in Immunology. 12, 707690.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients

    Bliddal, S., Banasik, Karina, Pedersen, Ole Birger Vesterager, Nissen, J., Cantwell, Lisa, Schwinn, M., Tulstrup, Morten Rytter, Westergaard, David, Ullum, H., Brunak, Søren, Tommerup, Niels, Feenstra, B., Geller, F., Ostrowski, Sisse Rye, Grønbæk, Kirsten, Nielsen, Claus Henrik, Nielsen, Susanne Dam & Feldt-Rasmussen, Ulla, 2021, In: Scientific Reports. 11, 13153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4

    Martín Monreal, M. T., Stripp, Alexandra, Massarenti, Laura, Mondal, S., Šenolt, L., Ødum, Niels, Nielsen, Michael Lund, Thompson, P. R., Nielsen, Claus Henrik & Damgaard, D., 2021, In: Frontiers in Immunology. 12, 11 p., 716250.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    CDX2 regulates interleukin-33 gene expression in intestinal epithelial cells (LS174T)

    Larsen, S., Seidelin, Jakob Benedict, Davidsen, J., Dahlgaard, K., Nielsen, Claus Henrik, Bennett, Eric Paul, Pedersen, O. B., Coskun, M. & Troelsen, J. T., 2021, In: FEBS Open Bio. 11, 6, p. 1638-1644

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Circulating antibodies against leukotoxin A as marker of periodontitis grades B and C and oral infection with Aggregatibacter actinomycetemcomitans

    Damgaard, Christian, Danielsen, Anne Katrine, Enevold, C., Reinholdt, J., Holmstrup, Palle, Nielsen, Claus Henrik & Massarenti, Laura, 2021, In: Journal of Periodontology. 92, 12, p. 1795-1804 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Complement split product C3c in saliva as biomarker for periodontitis and response to periodontal treatment

    Suell, Maria Grande, Midjord-Belstrøm, Daniel, Damgaard, Christian, Holmstrup, Palle, Thangaraj, S. S., Nielsen, Claus Henrik & Palarasah, Y., 2021, In: Journal of Periodontal Research. 56, 1, p. 27-33 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Objective and noninvasive biochemical markers in rheumatoid arthritis: where are we and where are we going?

    Bay-Jensen, A. C., Siebuhr, A. S., Damgaard, D., Drobinski, P., Thudium, C., Mortensen, J. & Nielsen, Claus Henrik, 2021, In: Expert Review of Proteomics. 18, 3, p. 159-175 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Periodontitis increases risk of viable bacteria in freshly drawn blood donations

    Damgaard, Christian, Sækmose, S. G., Nilsson, Carl Martin Peter, Kilian, Mogens, Nielsen, Claus Henrik & Holmstrup, Palle, 2021, In: Blood Transfusion. 19, 5, p. 376-383

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The Extracellular Polysaccharide Matrix of Pseudomonas aeruginosa Biofilms Is a Determinant of Polymorphonuclear Leukocyte Responses

    Rybtke, Morten Levin, Jensen, Peter Østrup, Nielsen, Claus Henrik & Tolker-Nielsen, Tim, 2021, In: Infection and Immunity. 89, 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2020
  31. Published

    Identification of Novel Native Autoantigens in Rheumatoid Arthritis

    Poulsen, T. B. G., Damgaard, D., Jørgensen, M. M., Senolt, L., Blackburn, J. M., Nielsen, Claus Henrik & Stensballe, A., 2020, In: Biomedicines. 8, 6, 13 p., 141.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Ruxolitinib and interferon-alpha 2 combination therapy for patients with polycythemia vera or myelofibrosis: a phase II study

    Sorensen, A. L., Mikkelsen, Stine Ulrik, Knudsen, T. A., Bjorn, M. E., Andersen, Christen Bertel L, Bjerrum, O. W., Brochmann, N., Patel, D. A., Gjerdrum, Lise Mette Rahbek, El Fassi, D., Kruse, T. A., Larsen, T. S., Mourits-Andersen, H. T., Nielsen, Claus Henrik, Ellervik, Christina, Pallisgaard, N., Thomassen, M., Kjaer, L., Skov, V. & Hasselbach, H. C., 2020, In: Haematologica. 105, 9, p. 2262-2272 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2019
  34. Published

    Ruxolitinib treatment reduces monocytic superoxide radical formation without affecting hydrogen peroxide formation or systemic oxidative nucleoside damage in myelofibrosis

    Bjørn, M. E., Brimnes, M. K., Gudbrandsdottir, S., Andersen, C. L., Poulsen, Henrik Enghusen, Henriksen, T., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, Oct 2019, In: Leukemia and Lymphoma. 60, 10, p. 2549-2557 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Porphyromonas gingivalis in saliva associates with chronic and aggressive periodontitis

    Damgaard, Christian, Danielsen, Anne Katrine, Enevold, C., Massarenti, Laura, Nielsen, Claus Henrik, Holmstrup, Palle & Midjord-Belstrøm, Daniel, 2019, In: Journal of Oral Microbiology. 11, 1, p. 1-9 9 p., 1653123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Assessment of peptidylarginine deiminase activity by ELISA using human fibrinogen as substrate

    Damgaard, D. & Nielsen, Claus Henrik, 2019, Autoantibodies: Methods and Protocols. Houen, G. (ed.). Humana Press, p. 239-242 4 p. (Methods in Molecular Biology, Vol. 1901).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  37. Associations between serum and plasma brain-derived neurotrophic factor and influence of storage time and centrifugation strategy

    Gejl, A. K., Enevold, C., Bugge, A., Andersen, M. S., Nielsen, Claus Henrik & Andersen, L. B., 2019, In: Scientific Reports. 9, 9 p., 9655.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Erythrocytes restrict microvesicle-induced production of reactive oxygen species by polymorphonuclear leukocytes

    Winberg, L. K., Rasmussen, N. S., Nielsen, Claus Henrik & Jacobsen, Søren, 2019, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 27, 7, p. 538-542 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Expanding the citrullinome of synovial fibrinogen from rheumatoid arthritis patients

    Sharma, M., Danigaard, D., Senolt, L., Svensson, B., Bay-Jensen, A., Nielsen, Claus Henrik & Hägglund, Per Mårten, 2019, In: Journal of Proteomics. 208, 103484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Inflammatory functional iron deficiency common in myelofibrosis, contributes to anaemia and impairs quality of life. From the Nordic MPN study Group

    Birgegard, G., Samuelsson, J., Ahlstrand, E., Ejerblad, E., Enevold, C., Ghanima, W., Hasselbalch, Hans Carl, Nielsen, Claus Henrik, Knutsen, H., Pedersen, Ole Birger Vesterager, Sørensen, A. & Andreasson, B., 2019, In: European Journal of Haematology. 102, 3, p. 235-240

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Peptidylarginine deiminase-4 gene polymorphisms are associated with systemic lupus erythematosus and lupus nephritis

    Massarenti, Laura, Enevold, C., Damgaard, D., Ødum, Niels, Nielsen, Claus Henrik & Jacobsen, Søren, 2019, In: Scandinavian Journal of Rheumatology. 48, 2, p. 133-140

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Prognostic role of genetic polymorphisms of the interleukin-6 signaling pathway in patients with severe heart failure

    Hansen, Peter Riis, Nelveg-Kristensen, K. E., Rasmussen, H. B., Torp-Pedersen, C., Køber, Lars Valeur, Nielsen, Claus Henrik & Enevold, C., 2019, In: Pharmacogenomics Journal. 19, p. 428-437

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Release of active peptidylarginine deiminase into the circulation during acute inflammation induced by coronary artery bypass surgery

    Vejlstrup, A., Møller, A. M., Nielsen, Claus Henrik & Damgaard, D., 2019, In: Journal of Inflammation Research. 12, p. 137-144

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. 2018
  45. Published

    Safety and efficacy of combination therapy of interferon-α2 and ruxolitinib in polycythemia vera and myelofibrosis

    Mikkelsen, Stine Ulrik, Kjaer, L., Bjørn, M. E., Knudsen, T. A., Sørensen, A. L., Andersen, Christen Bertel L, Bjerrum, O. W., Brochmann, N., Fassi, Daniel El , Kruse, T. A., Larsen, T. S., Mourits-Andersen, H. T., Nielsen, Claus Henrik, Pallisgaard, N., Thomassen, M., Skov, V. & Hasselbalch, Hans Carl, Aug 2018, In: Cancer Medicine. 7, 8, p. 3571-3581 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Reconstitution of Th17, Tc17 and Treg cells after paediatric haematopoietic stem cell transplantation: Impact of interleukin-7

    Kielsen, K., Ryder, L. P., Lennox-Hvenekilde, D., Gad, M., Nielsen, Claus Henrik, Heilmann, C., Ifversen, M., Pedersen, Anders Elm & Muller, Klaus, Feb 2018, In: Immunobiology. 223, 2, p. 220-226 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3

    Damgaard, D., Bawadekar, M., Senolt, L., Stensballe, A., Shelef, M. A. & Nielsen, Claus Henrik, 2018, In: PLoS ONE. 13, 8, p. 1-14 e0203214.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Surfactant Protein D Deficiency Aggravates Cigarette Smoke-Induced Lung Inflammation by Upregulation of Ceramide Synthesis

    Pilecki, B., Wulf-Johansson, H., Støttrup, C., Jørgensen, P. T., Djiadeu, P., Nexøe, A. B., Schlosser, A., Hansen, S. W. K., Madsen, J., Clark, H. W., Nielsen, Claus Henrik, Vestbo, J., Palaniyar, N., Holmskov, U. & Sorensen, G. L., 2018, In: Frontiers in Immunology. 9, 12 p., 3013.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. 2017
  50. Published

    Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

    Damgaard, D., Bjørn, M. E., Jensen, Peter Østrup & Nielsen, Claus Henrik, Dec 2017, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 1203-1208 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Microparticles from patients with systemic lupus erythematosus induce production of reactive oxygen species and degranulation of polymorphonuclear leukocytes

    Winberg, L. K., Jacobsen, Søren & Nielsen, Claus Henrik, 17 Oct 2017, In: Arthritis Research & Therapy. 19, 10 p., 230.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    The flame retardant DE-71 (a mixture of polybrominated diphenyl ethers) inhibits human differentiated thyroid cell function in vitro

    Kronborg, T. M., Hansen, J. F., Rasmussen, Å. K., Vorkamp, K., Nielsen, Claus Henrik, Frederiksen, M., Hofman-Bang, J., Hahn, Christoffer Holst, Ramhøj, L. & Feldt-Rasmussen, Ulla, Jun 2017, In: PloS one. 12, 6, 18 p., e0179858.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Cholesterol crystals enhance TLR2-and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis

    Køllgaard, T. M. S., Enevold, Christian, Bendtzen, K., Hansen, Peter Riis, Givskov, Michael, Holmstrup, Palle & Nielsen, Claus Henrik, 24 Feb 2017, In: P L o S One. 12, 2, 14 p., 0172773.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician

    Holmstrup, Palle, Damgaard, Christian, Olsen, I., Klinge, B., Flyvbjerg, A., Nielsen, Claus Henrik & Hansen, Peter Riis, 2017, In: Journal of Oral Microbiology. 9, 1, 14 p., 1332710.

    Research output: Contribution to journal › Review › Research › peer-review

  55. Published

    Immunoglobulin G antibodies against Porphyromonas gingivalis or Aggregatibacter actinomycetemcomitans in cardiovascular disease and periodontitis

    Damgaard, Christian, Reinholdt, J., Enevold, C., Fiehn, Nils-Erik, Nielsen, Claus Henrik & Holmstrup, Palle, 2017, In: Journal of Oral Microbiology. 9, 1, 1374154.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    In vitro complement activation, adherence to red blood cells and induction of mononuclear cell cytokine production by four strains of Aggregatibacter actinomycetemcomitans with different fimbriation and expression of leukotoxin

    Damgaard, Christian, Reinholdt, J., Palarasah, Y., Enevold, Christian, Nielsen, C., Brimnes, M. K., Holmstrup, Palle & Nielsen, Claus Henrik, 2017, In: Journal of Periodontal Research. 52, 3, p. 485-496 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Komorbiditet ved marginal parodontitis: To sider af samme sag?

    Holmstrup, Palle, Damgaard, Christian, Olsen, I., Klinge, B., Flyvbjerg, A., Nielsen, Claus Henrik & Hansen, Peter Riis, 2017, In: Tandlaegebladet. 121, 1, p. 52-61

    Research output: Contribution to journal › Review › Research › peer-review

  58. Published

    Porphyromonas gingivalis-induced production of reactive oxygen species, tumor necrosis factor-α, interleukin-6, CXCL8 and CCL2 by neutrophils from localized aggressive periodontitis and healthy donors: modulating actions of red blood cells and resolvin E1

    Damgaard, Christian, Kantarci, A., Holmstrup, Palle, Hasturk, H., Nielsen, Claus Henrik & Van Dyke, T. E., 2017, In: Journal of Periodontal Research. 52, 2, p. 246-254 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Recent advances in understanding autoimmune thyroid disease: the tallest tree in the forest of polyautoimmunity

    Bliddal, S., Nielsen, Claus Henrik & Feldt-Rasmussen, Ulla, 2017, In: F1000Research. 6, 12 p., 1776.

    Research output: Contribution to journal › Review › Research › peer-review

  60. 2016
  61. Published

    Reduced glutathione as a physiological co-activator in the activation of peptidylarginine deiminase

    Damgaard, D., Bjørn, M. E., Steffensen, Maria Abildgaard, Pruijn, G. J. M. & Nielsen, Claus Henrik, 5 May 2016, In: Arthritis Research & Therapy. 18, 1, p. 102 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Lactobacillus reuteri supplements do not affect salivary IgA or cytokine levels in healthy subjects: A randomized, double-blind, placebo-controlled cross-over trial

    Jørgensen, Mette Rose, Keller, M. K., Kragelund, C., Hamberg, K., Ericson, D., Nielsen, Claus Henrik & Twetman, Svante, 22 Apr 2016, In: Acta Odontologica Scandinavica. 74, 5, p. 399-404 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Increased levels of peptidylarginine deiminase 2 in synovial fluid from anti-CCP-positive rheumatoid arthritis patients: Association with disease activity and inflammatory markers

    Damgaard, D., Senolt, L. & Nielsen, Claus Henrik, 15 Feb 2016, In: Rheumatology. 55, 5, p. 918-927 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Influence of complement on neutrophil extracellular trap release induced by bacteria

    Palmer, L. J., Damgaard, Christian, Holmstrup, Palle & Nielsen, Claus Henrik, Feb 2016, In: Journal of Periodontal Research. 51, 1, p. 70-76 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Linkage Between Periodontal Disease and Rheumatoid Arthritis

    Holmstrup, Palle & Nielsen, Claus Henrik, Jan 2016, Oral Infections and General Health: From Molecule to Chairside. Pedersen, A. M. L. (ed.). 1 ed. Heidelberg: Springer, p. 45-51 6 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  66. Published

    Myelin Basic Protein-Induced Production of Tumor Necrosis Factor-α and Interleukin-6, and Presentation of the Immunodominant Peptide MBP85-99 by B Cells from Patients with Relapsing-Remitting Multiple Sclerosis

    Nielsen, Claus Henrik, Börnsen, L., Sellebjerg, Finn Thorup & Brimnes, M. K., Jan 2016, In: PLOS ONE. 11, 1, 13 p., e0146971.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Pseudomonas aeruginosa Microcolonies in Coronary Thrombi from Patients with ST-Segment Elevation Myocardial Infarction

    Hansen, G. M., Midjord-Belstrøm, Daniel, Nilsson, Carl Martin Peter, Helqvist, S., Nielsen, Claus Henrik, Holmstrup, Palle, Tolker-Nielsen, Tim, Givskov, Michael & Hansen, Peter Riis, 2016, In: P L o S One. 11, 12, 13 p., e0168771.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Effects of the Commercial Flame Retardant Mixture DE-71 on Cytokine Production by Human Immune Cells

    Mynster Kronborg, T., Hansen, J. F., Nielsen, Claus Henrik, Ramhøj, L., Frederiksen, M., Vorkamp, K. & Feldt-Rasmussen, Ulla, 2016, In: PLOS ONE. 11, 4, 13 p., e0154621.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Non-Medical Switch from Originator to Biosimilar Infliximab in Patients with Inflammatory Arthritis: Impact on s-Infliximab and Antidrug-Antibodies. Results from the Danish Rheumatologic Biobank and the Danbio Registry

    Glintborg, B., Kringelbach, T. M., Høgdall, E. V. S., Sørensen, I. J., Jensen, D. V., Loft, A. G., Hendricks, O., Hansen, I. M. J., Linauskas, A., Kristensen, S., Lindegaard, H., Nordin, H., Bolstad, N., Warren, D., Gehin, J., Goll, G. L., Grøn, K. L., Eng, G., Enevold, C., Nielsen, C. H. & 2 others, Johansen, Julia Sidenius & Hetland, Merete Lund, 2016, In: Arthritis & Rheumatology. 68, S10, 4 p., 1997.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  70. Published

    Phthalates Are Metabolised by Primary Thyroid Cell Cultures but Have Limited Influence on Selected Thyroid Cell Functions In Vitro

    Hansen, J. F., Brorson, M. M., Boas, M., Frederiksen, H., Nielsen, Claus Henrik, Lindström, E. S., Hofman-Bang, J., Hartoft-Nielsen, M., Frisch, T., Main, Katharina Maria, Bendtzen, K., Rasmussen, Å. K. & Feldt-Rasmussen, Ulla, 2016, In: P L o S One. 11, 3, 16 p., e0151192.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. 2015
  72. Published

    Telomerase Inhibitor Imetelstat in Essential Thrombocythemia and Myelofibrosis

    Bjørn, M. E., Nielsen, Claus Henrik & Hasselbalch, H. C., 24 Dec 2015, In: New England Journal of Medicine. 373, 26, p. 2579-80 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  73. Published

    Dietary exposure to benzoxazinoids enhances bacteria-induced monokine responses by peripheral blood mononuclear cells

    Damgaard, D., Jensen, B. M., Palarasah, Y., Nielsen, M. F. B., Adhikari, K. B., Schnoor, H. J., Juel-Berg, N., Poulsen, Lars K., Fomsgaard, I. S. & Nielsen, Claus Henrik, Nov 2015, In: Molecular Nutrition & Food Research (Online). 59, 11, p. 2190-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Benzoxazinoids: Cereal phytochemicals with putative therapeutic and health-protecting properties

    Adhikari, K. B., Tanwir, F., Gregersen, P. L., Steffensen, S. K., Jensen, B. M., Poulsen, Lars K., Nielsen, Claus Henrik, Høyer, S., Borre, M. & Fomsgaard, I. S., Jul 2015, In: Molecular Nutrition & Food Research. 59, 7, p. 1324-1338 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  75. Published

    The complement system and its role in the pathogenesis of periodontitis: current concepts

    Damgaard, Christian, Holmstrup, Palle, Van Dyke, T. E. & Nielsen, Claus Henrik, Jun 2015, In: Journal of Periodontal Research. 50, 3, p. 283-293 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  76. Published

    Altered balance between self-reactive T helper (Th)17 cells and Th10 cells and between full-length forkhead box protein 3 (FoxP3) and FoxP3 splice variants in Hashimoto's thyroiditis

    Kristensen, B., Hegedüs, L., Madsen, H. O., Smith, T. J. & Nielsen, Claus Henrik, Apr 2015, In: Clinical and Experimental Immunology. 180, 1, p. 58-69 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Viable Bacteria Associated with Red Blood Cells and Plasma in Freshly Drawn Blood Donations

    Damgaard, Christian, Magnussen, K., Enevold, Christian, Nilsson, Carl Martin Peter, Tolker-Nielsen, Tim, Holmstrup, Palle & Nielsen, Claus Henrik, 9 Mar 2015, In: P L o S One. 10, 3, p. 1-9 9 p., e0120826.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Absence of Bacteria on Coronary Angioplasty Balloons from Unselected Patients: Results with Use of a High Sensitivity Polymerase Chain Reaction Assay

    Hansen, G. M., Nilsson, M., Nielsen, Claus Henrik, Holmstrup, Palle, Helqvist, S., Tolker-Nielsen, Tim, Givskov, Michael & Hansen, Peter Riis, 2015, In: PloS one. 10, 12, p. 1-11 11 p., e0145657.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Differentiation of salivary bacterial profiles of subjects with periodontitis and dental caries

    Midjord-Belstrøm, Daniel, Fiehn, Nils-Erik, Nielsen, Claus Henrik, Klepac-Ceraj, V., Paster, B. J., Twetman, Svante & Holmstrup, Palle, 2015, In: Journal of Oral Microbiology. 7, p. 1-5 5 p., 27429.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Influence of Phthalates on in vitro Innate and Adaptive Immune Responses

    Hansen, J. F., Nielsen, Claus Henrik, Brorson, M. M., Frederiksen, H., Hartoft-Nielsen, M., Rasmussen, Å. K., Bendtzen, K. & Feldt-Rasmussen, Ulla, 2015, In: P L o S One. 10, 6, 13 p., e0131168.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Rapid eye movement-sleep is reduced in patients with acute uncomplicated diverticulitis—an observational study

    Huang, C., Alamili, M., Nielsen, Claus Henrik, Rosenberg, Jacob & Gögenur, I., 2015, In: PeerJ. 3, p. 1-13 13 p., 1146.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Smoking is associated with increased levels of extracellular peptidylarginine deiminase 2 (PAD2) in the lungs

    Damgaard, D., Friberg Bruun Nielsen, M., Quisgaard Gaunsbaek, M., Palarasah, Y., Svane-Knudsen, V. & Nielsen, Claus Henrik, 2015, In: Clinical and Experimental Rheumatology. 33, 3, p. 405-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. 2014
  84. Published

    Preoperative methylprednisolone enhances recovery after endovascular aortic repair: a randomized, double-blind, placebo-controlled clinical trial

    de la Motte, L., Kehlet, Henrik, Vogt, K., Nielsen, Claus Henrik, Groenvall, J. B., Nielsen, H. B., Andersen, A., Schroeder, T. V. & Lönn, Lars, Sep 2014, In: Annals of Surgery. 260, 3, p. 540-549

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Interleukin-6-receptor polymorphisms rs12083537, rs2228145, and rs4329505 as predictors of response to tocilizumab in rheumatoid arthritis

    Enevold, C., Baslund, B., Linde, L., Josephsen, N. L., Tarp, U., Lindegaard, H., Jacobsen, Søren & Nielsen, Claus Henrik, Aug 2014, In: Pharmacogenetics and Genomics. 24, 8, p. 401-405 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  86. Published

    A matrix of cholesterol crystals, but not cholesterol alone, primes human monocytes/macrophages for excessive endotoxin-induced production of tumor necrosis factor-alpha. Role in atherosclerotic inflammation?

    Bendtzen, K., Christensen, O., Nielsen, Claus Henrik & Holmstrup, Palle, Jun 2014, In: Discovery Medicine. 17, 96, p. 309-12 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Mulig sammenhæng mellem marginal parodontitis og iskæmisk hjertesygdom

    Hansen, G. M., Holmstrup, Palle, Tolker-Nielsen, Tim, Køllgaard, T., Nielsen, Claus Henrik, Givskov, Michael & Hansen, Peter Riis, 28 Apr 2014, In: Ugeskrift for Laeger. 176, 18, p. 1752-1754 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Generation of monoclonal antibodies against peptidylarginine deiminase 2 (PAD2) and development of a PAD2-specific enzyme-linked immunosorbent assay

    Damgaard, D., Palarasah, Y., Skjødt, K., Catrina, A. I., Hensen, S. M. M., Pruijn, G. J. M. & Nielsen, Claus Henrik, Mar 2014, In: Journal of Immunological Methods. 405, p. 15-22 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Differences in bacterial saliva profile between periodontitis patients and a control cohort

    Midjord-Belstrøm, Daniel, Fiehn, Nils-Erik, Nielsen, Claus Henrik, Kirkby, N., Twetman, Svante, Klepac-Ceraj, V., Paster, B. J. & Holmstrup, Palle, Feb 2014, In: Journal of Clinical Periodontology. 41, 2, p. 104-12 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Bacterial profiles of saliva in relation to diet, lifestyle factors, and socioeconomic status

    Midjord-Belstrøm, Daniel, Holmstrup, Palle, Nielsen, Claus Henrik, Kirkby, N., Twetman, Svante, Heitmann, Berit, Klepac-Ceraj, V., Paster, B. J. & Fiehn, Nils-Erik, 2014, In: Journal of Oral Microbiology. 6, p. 1-9 9 p., 23609.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Demonstration of extracellular peptidylarginine deiminase (PAD) activity in synovial fluid of patients with rheumatoid arthritis using a novel assay for citrullination of fibrinogen

    Damgaard, D., Senolt, L., Nielsen, M. F., Pruijn, G. J. & Nielsen, Claus Henrik, 2014, In: Arthritis Research & Therapy (Print). 16, 6, p. 1-7 7 p., 498.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Genetic polymorphisms of dsRNA ligating pattern recognition receptors TLR3, MDA5, and RIG-I. Association with systemic lupus erythematosus and clinical phenotypes

    Enevold, Christian, Kjaer, L., Nielsen, Claus Henrik, Voss, A., Jacobsen, R. S., Hermansen, M. F., Redder, L., Oturai, A. B., Jensen, P. E., Bendtzen, K. & Jacobsen, Søren, 2014, In: Rheumatology International. 34, 10, p. 1401-1408 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Single nucleotide polymorphisms in genes encoding toll-like receptors 7, 8 and 9 in Danish patients with systemic lupus erythematosus

    Enevold, Christian, Nielsen, Claus Henrik, Jacobsen, R. S., Hermansen, M. F., Molbo, Drude, Avlund, K., Bendtzen, K. & Jacobsen, Søren, 2014, In: Molecular Biology Reports. 41, 9, p. 5755-5763 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Uptake and presentation of myelin basic protein by normal human b cells

    Brimnes, M. K., Hansen, B. E., Nielsen, L. K., Dziegiel, Morten Hanefeld & Nielsen, Claus Henrik, 2014, In: PLOS ONE. 9, 11, 10 p., e113388.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. 2013
  96. Published

    Activated platelets enhance IL-10 secretion and reduce TNF-α secretion by monocytes

    Gudbrandsdottir, S., Hasselbalch, H. C. & Nielsen, Claus Henrik, 15 Oct 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 8, p. 4059-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Rituximab and dexamethasone vs dexamethasone monotherapy in newly diagnosed patients with primary immune thrombocytopenia

    Gudbrandsdottir, S., Birgens, H. S., Frederiksen, H., Jensen, B. A., Jensen, M. K., Kjeldsen, L., Klausen, T. W., Larsen, H., Mourits-Andersen, H. T., Nielsen, Claus Henrik, Nielsen, O. J., Plesner, T., Pulczynski, S., Rasmussen, I. H., Rønnov-Jessen, D. & Hasselbalch, H. C., 14 Mar 2013, In: Blood. 121, 11, p. 1976-81 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. 2012
  99. Published

    Triterpene Acids from Rose Hip Powder Inhibit Self-antigen- and LPS-induced Cytokine Production and CD4(+) T-cell Proliferation in Human Mononuclear Cell Cultures

    Saaby, Lasse & Nielsen, Claus Henrik, Aug 2012, In: Phytotherapy Research. 26, 8, p. 1142-1147 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Does a causal relation between cardiovascular disease and periodontitis exist?

    Midjord-Belstrøm, Daniel, Damgaard, Christian, Nielsen, Claus Henrik & Holmstrup, Palle, May 2012, In: Microbes and Infection. 14, 5, p. 411-8 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  101. Published

    The cellular cancer resistance of the SR/CR mouse

    Koch, J., Hau, Jann, Jensen, Henrik Elvang, Nielsen, Claus Henrik & Rieneck, K., 2012, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 120, 12, p. 974-987 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. 2011
  103. Published

    Interferon-beta increases systemic BAFF levels in multiple sclerosis without increasing autoantibody production

    Hedegaard, C. J., Sellebjerg, Finn Thorup, Krakauer, M., Hesse, D., Bendtzen, K. & Nielsen, Claus Henrik, 1 May 2011, In: Multiple Sclerosis. 17, 5, p. 567-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  104. Published

    Monozygotic twin pairs discordant for Hashimoto's thyroiditis share a high proportion of thyroid peroxidase autoantibodies to the immunodominant region A. Further evidence for genetic transmission of epitopic "fingerprints"

    Brix, T. H., Hegedüs, L., Gardas, A., Banga, J. P. & Nielsen, Claus Henrik, 1 May 2011, In: Autoimmunity. 44, 3, p. 188-94 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  105. Published

    The atherogenic bacterium Porphyromonas gingivalis evades circulating phagocytes by adhering to erythrocytes

    Midjord-Belstrøm, Daniel, Holmstrup, Palle, Damgaard, Christian, Borch, T. S., Skjødt, M., Bendtzen, K. & Nielsen, Claus Henrik, 1 Apr 2011, In: Infection and Immunity. 79, 4, p. 1559-65 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  106. Published

    The HLA-DP2 protein binds the immunodominant epitope from myelin basic protein, MBP85-99, with high affinity

    Hansen, B. E., Nielsen, Claus Henrik, Madsen, H. O., Ryder, L. P., Jakobsen, B. K. & Svejgaard, A., 1 Mar 2011, In: HLA. 77, 3, p. 229-34 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  107. Published

    Nye behandlingsmuligheder ved primær immun trombocytopeni

    Gudbrandsdottir, S., Frederiksen, H., Birgens, H. S., Nielsen, Claus Henrik, Nielsen, O. J., Stentoft, J. & Hasselbalch, H. C., 24 Jan 2011, In: Ugeskrift for Laeger. 173, 4, p. 271-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  108. Published

    Patofysiologien ved primær immun trombocytopeni

    Gudbrandsdottir, S., Frederiksen, H., Birgens, H. S., Nielsen, Claus Henrik, Nielsen, O. J., Stentoft, J. & Hasselbalch, H. C., 24 Jan 2011, In: Ugeskrift for Laeger. 173, 4, p. 274-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  109. Published

    Targeted biological therapies for Graves' disease and thyroid-associated ophthalmopathy. Focus on B-cell depletion with Rituximab

    Hegedüs, L., Smith, T. J., Douglas, R. S., Nielsen, Claus Henrik & Smith, T. J., 1 Jan 2011, In: Clinical Endocrinology. 74, 1, p. 1-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  110. Published

    Glatiramer acetate antibodies, gene expression and disease activity in multiple sclerosis

    Sellebjerg, Finn Thorup, Hedegaard, C. J., Krakauer, M., Hesse, D., Lund, H., Nielsen, Claus Henrik, Søndergaard, H. B. & Sørensen, Per Soelberg, 2011, In: Multiple Sclerosis.

    Research output: Contribution to journal › Journal article › Research › peer-review

  111. Published

    Systemic adverse events following rituximab therapy in patients with Graves' disease

    Fassi, Daniel El , Nielsen, Claus Henrik, Junker, M. P., Hasselbalch, H. C. & Hegedüs, L., 2011, In: Journal of Endocrinological Investigation. 34, 7, p. e163-7

    Research output: Contribution to journal › Journal article › Research › peer-review

  112. Published

    Variation in NOD2 augments Th2- and Th17 responses to myelin basic protein in multiple sclerosis

    Hedegaard, C. J., Enevold, C., Sellebjerg, Finn Thorup, Bendtzen, K. & Nielsen, Claus Henrik, 2011, In: P L o S One. 6, 5, p. e20253

    Research output: Contribution to journal › Journal article › Research › peer-review

  113. 2010
  114. Published

    Enhancement of natural killer cell activity in healthy subjects by Immulina®, a Spirulina extract enriched for Braun-type lipoproteins

    Nielsen, Claus Henrik, Balachandran, P., Christensen, O., Pugh, N. D., Tamta, H., Sufka, K. J., Wu, X., Walsted, A., Schjørring-Thyssen, M., Enevold, Christian & Pasco, D. S., 1 Nov 2010, In: Planta Medica. 76, 16, p. 1802-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  115. Published

    Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

    Maltesen, H. R., Nielsen, Claus Henrik, Dalbøge, C. S. & Baslund, B., 1 Nov 2010, In: Rheumatology. 49, 11, p. 2037-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  116. Published

    Monozygotic twin pairs discordant for Hashimoto's thyroiditis share a high proportion of thyroid peroxidase autoantibodies to the immunodominant region A. Further evidence for genetic transmission of epitopic “fingerprints”

    Brix, T. H., Hegedüs, L., Gardas, A., Banga, J. P. & Nielsen, Claus Henrik, 1 Oct 2010, In: Autoimmunity.

    Research output: Contribution to journal › Journal article › Research › peer-review

  117. Published

    In vitro cytokine responses to periodontal pathogens: generalized aggressive periodontitis is associated with increased IL-6 response to Porphyromonas gingivalis

    Borch, T. S., Holmstrup, P., Bendtzen, K. & Nielsen, Claus Henrik, 1 Jun 2010, In: Scandinavian Journal of Immunology. 71, 6, p. 440-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  118. Published

    Cell saver for on-pump coronary operations reduces systemic inflammatory markers: a randomized trial

    Damgaard, Sune, Nielsen, Claus Henrik, Andersen, L. W., Bendtzen, K., Tvede, M. & Steinbrüchel, D., 1 May 2010, In: Annals of Thoracic Surgery. 89, 5, p. 1511-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  119. Published

    The self-antigen, thyroglobulin, induces antigen-experienced CD4+ T cells from healthy donors to proliferate and promote production of the regulatory cytokine, interleukin-10, by monocytes

    Nielsen, Claus Henrik, Galdiers, M. P., Hedegaard, C. J. & Leslie, R. G. Q., 1 Feb 2010, In: Immunology. 129, 2, p. 291-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  120. 2009
  121. Published

    Evidence of orbital B and T cell depletion after rituximab therapy in Graves' ophthalmopathy

    Nielsen, J. F., El Fassi, D., Nielsen, Claus Henrik, Hegedüs, L., Lauer, S. A., Silkiss, R. Z., Prause, J. U., Nielsen, J. F., Fassi, Daniel El , Nielsen, C. H., Hegedüs, L., Lauer, S. A., Silkiss, R. Z. & Prause, J. U., 1 Nov 2009, In: Acta Ophthamologica (Online). 87, 8, p. 927-9 3 p.

    Research output: Contribution to journal › Journal article › Research

  122. Published

    Biomimetic triblock copolymer membrane arrays: A stable template for functional membrane proteins

    Gonzalez-Perez, Alfredo, Stibius, K. B., Vissing, T., Nielsen, Claus Henrik & Mouritsen, Ole G., 15 Sep 2009, In: Langmuir. 25, 18, p. 10447-10450 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  123. Published

    Autoantibodies to myelin basic protein (MBP) in healthy individuals and in patients with multiple sclerosis: a role in regulating cytokine responses to MBP

    Hedegaard, C. J., Chen, N., Sellebjerg, Finn Thorup, Sørensen, Per Soelberg, Leslie, R. G. Q., Bendtzen, K. & Nielsen, Claus Henrik, 1 Sep 2009, In: Immunology. 128, 1 Suppl, p. e451-61

    Research output: Contribution to journal › Journal article › Research › peer-review

  124. Published

    A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase

    Nielsen, Claus Henrik, Brix, T. H., Leslie, R. G. Q. & Hegedüs, L., 2009, In: Clinical Immunology. 133, 2, p. 218-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  125. Published

    Decreased interleukin-2 responses to Fusobacterium nucleatum and Porphyromonas gingivalis in generalized aggressive periodontitis

    Borch, T. S., Løbner, M., Bendtzen, K., Holmstrup, Palle & Nielsen, Claus Henrik, 2009, In: Journal of Periodontology. 80, 5, p. 800-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  126. Published

    Spontaneous complement activation on human B cells results in localized membrane depolarization and the clustering of complement receptor type 2 and C3 fragments

    Løbner, M., Leslie, R. G. Q., Prodinger, W. M. & Nielsen, Claus Henrik, 2009, In: Immunology. 128, 1 Suppl, p. e661-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  127. 2008
  128. Published

    Epitope recognition patterns of thyroid peroxidase autoantibodies in healthy individuals and patients with Hashimoto's thyroiditis*

    Nielsen, Claus Henrik, Brix, T. H., Gardas, A., Banga, J. P. & Hegedüs, L., 1 Oct 2008, In: Clinical Endocrinology. 69, 4, p. 664-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  129. Published

    T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

    Hedegaard, C. J., Krakauer, M., Bendtzen, K., Lund, H., Sellebjerg, Finn Thorup & Nielsen, Claus Henrik, 1 Oct 2008, In: Immunology. 125, 2, p. 161-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  130. Published

    The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis

    Hedegaard, C. J., Krakauer, M., Bendtzen, K., Sørensen, Per Soelberg, Sellebjerg, Finn Thorup & Nielsen, Claus Henrik, 1 Oct 2008, In: Clinical Immunology. 129, 1, p. 80-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  131. Published

    Application of new therapies in Graves' disease and thyroid-associated ophthalmopathy: animal models and translation to human clinical trials

    Banga, J. P., Nielsen, Claus Henrik, Gilbert, J. A., Fassi, Daniel El & Hegedus, L., 1 Sep 2008, In: Thyroid. 18, 9, p. 973-81 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  132. Published

    Biologiske behandlingsmuligheder ved Graves' oftalmopati

    Fassi, Daniel El , Nielsen, Claus Henrik & Hegedüs, L., 9 Jun 2008, In: Ugeskrift for Laeger. 170, 24, p. 2128-30 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  133. Published

    Nye behandlinger af Graves' sygdom med fokus på det B-lymfocyt-depleterende antistof rituximab

    Nielsen, Claus Henrik, Fassi, Daniel El & Hegedüs, L., 9 Jun 2008, In: Ugeskrift for Laeger. 170, 24, p. 2131-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  134. Published

    Enhancement of human adaptive immune responses by administration of a high-molecular-weight polysaccharide extract from the cyanobacterium Arthrospira platensis

    Løbner, M., Walsted, A., Larsen, R., Bendtzen, K. & Nielsen, Claus Henrik, 1 Jun 2008, In: Journal of Medicinal Food. 11, 2, p. 313-22 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  135. Published

    Ulcerative colitis following B lymphocyte depletion with rituximab in a patient with Graves' disease

    Fassi, Daniel El , Nielsen, Claus Henrik, Kjeldsen, J. B., Clemmensen, O. & Hegedüs, L., 1 May 2008, In: Gut. 57, 5, p. 714-5 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  136. Published

    Reduced folate carrier polymorphism determines methotrexate uptake by B cells and CD4+ T cells

    Baslund, B., Gregers, J. & Nielsen, Claus Henrik, 1 Apr 2008, In: Rheumatology. 47, 4, p. 451-3 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  137. Published

    Application of new therapies in Graves' disease and thyroid-associated ophthalmopathy: animal models and translation to human clinical trialsTumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease

    Banga, J. P., Gilbert, J. A., El, F. D., Hegedus, L. & Nielsen, Claus Henrik, 2008, In: Thyroid. 18, 9, p. 973-981 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  138. Published

    B-lymfocytdepletring og andre biologiske behandlingsmuligheder ved Graves' oftalmopatiTumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease

    El, F. D., Hegedus, L. & Nielsen, Claus Henrik, 2008, In: Ugeskrift for læger. 170, 24, p. 2128-2130 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  139. Published

    Reduced folate carrier polymorphism determines methotrexate uptake by B cells and CD4+ T cellsTumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease

    Baslund, B., Gregers, J. & Nielsen, Claus Henrik, 2008, In: Rheumatology.(Oxford). 47, 4, p. 451-453 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  140. Published

    Treatment of Graves' disease with rituximab specifically reduces the production of thyroid stimulating autoantibodies

    Fassi, Daniel El , Banga, J. P., Gilbert, J. A., Padoa, C., Hegedüs, L. & Nielsen, Claus Henrik, 2008, In: Clinical Immunology. 130, 3, p. 252-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  141. Published

    Ulcerative colitis following B lymphocyte depletion with rituximab in a patient with Graves' diseaseTumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease

    El, F. D., Kjeldsen, J., Clemmensen, O., Hegedus, L. & Nielsen, Claus Henrik, 2008, In: Gut. 57, 5, p. 714-715 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  142. 2007
  143. Published

    Evidence of intrathyroidal B-lymphocyte depletion after rituximab therapy in a patient with Graves' disease

    Fassi, Daniel El , Clemmensen, O., Nielsen, Claus Henrik, Silkiss, R. Z. & Hegedüs, L., 1 Oct 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 10, p. 3762-3 2 p.

    Research output: Contribution to journal › Journal article › Research

  144. Published

    B-cell depletion with rituximab in the treatment of autoimmune diseases. Graves' ophthalmopathy the latest addition to an expanding family

    Nielsen, Claus Henrik, Fassi, Daniel El , Hasselbalch, H. K., Bendtzen, K. & Hegedüs, L., 1 Jul 2007, In: Expert Opinion on Biological Therapy. 7, 7, p. 1061-78 18 p.

    Research output: Contribution to journal › Journal article › Research

  145. Published

    B lymphocyte depletion with the monoclonal antibody rituximab in Graves' disease: a controlled pilot study

    Fassi, Daniel El , Nielsen, Claus Henrik, Bonnema, S. J., Hasselbalch, H. K. & Hegedüs, L., 1 May 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 5, p. 1769-72 4 p.

    Research output: Contribution to journal › Journal article › Research

  146. Published

    Gene expression profiling in autoimmune diseases: chronic inflammation or disease specific patterns?

    Bovin, L. F., Brynskov, J., Hegedüs, L., Jess, T., Nielsen, Claus Henrik & Bendtzen, K., 1 May 2007, In: Autoimmunity. 40, 3, p. 191-201 11 p.

    Research output: Contribution to journal › Journal article › Research

  147. Published

    Methotrexate induces poly(ADP-ribose) polymerase-dependent, caspase 3-independent apoptosis in subsets of proliferating CD4+ T cells

    Nielsen, Claus Henrik, Albertsen, L., Bendtzen, K. & Baslund, B., 1 May 2007, In: Clinical and Experimental Immunology. 148, 2, p. 288-95 8 p.

    Research output: Contribution to journal › Journal article › Research

  148. Published

    Production of interleukin (IL)-5 and IL-10 accompanies T helper cell type 1 (Th1) cytokine responses to a major thyroid self-antigen, thyroglobulin, in health and autoimmune thyroid disease

    Nielsen, Claus Henrik, Hegedüs, L., Rieneck, K., Moeller, A. C., Leslie, R. G. Q. & Bendtzen, K., 1 Feb 2007, In: Clinical and Experimental Immunology. 147, 2, p. 287-95 9 p.

    Research output: Contribution to journal › Journal article › Research

  149. 2006
  150. Published

    Rituximab (MabThera) til behandling af aktiv reumatoid artritis

    Fassi, Daniel El , Nielsen, Claus Henrik & Bendtzen, K., 20 Nov 2006, In: Ugeskrift for Laeger. 168, 47, p. 4079-81 3 p.

    Research output: Contribution to journal › Journal article › Research

  151. Published

    Increased plasma levels of IL-6 in bacteremic periodontis patients after scaling

    Forner, L., Nielsen, Claus Henrik, Bendtzen, K., Larsen, Tove & Holmstrup, Palle, 1 Oct 2006, In: Journal of Clinical Periodontology. 33, 10, p. 724-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  152. Published

    Treatment-resistant severe, active Graves' ophthalmopathy successfully treated with B lymphocyte depletion

    Fassi, Daniel El , Nielsen, Claus Henrik, Hasselbalch, H. K. & Hegedüs, L., 1 Jul 2006, In: Thyroid. 16, 7, p. 709-10 2 p.

    Research output: Contribution to journal › Journal article › Research

  153. Published

    Class switch recombination in selective IgA-deficient subjects

    Jensen, L. H., Ryder, L. P., Nielsen, L. K., Nielsen, Claus Henrik & Poulsen, Lars K., 1 Jun 2006, In: Clinical and Experimental Immunology. 144, 3, p. 458-66 9 p.

    Research output: Contribution to journal › Journal article › Research

  154. Published

    Surfactant protein D is proatherogenic in mice

    Sorensen, G. L., Madsen, J., Kejling, K., Tornoe, I., Nielsen, O., Townsend, P., Poulain, F., Nielsen, Claus Henrik, Reid, K. B. M., Hawgood, S., Falk, E. & Holmskov, U., 1 Jun 2006, In: American Journal of Physiology: Heart and Circulatory Physiology. 290, 6, p. H2286-94

    Research output: Contribution to journal › Journal article › Research

  155. Published

    The rationale for B lymphocyte depletion in Graves' disease. Monoclonal anti-CD20 antibody therapy as a novel treatment option

    Fassi, Daniel El , Nielsen, Claus Henrik, Hasselbalch, H. K. & Hegedüs, L., 1 May 2006, In: European Journal of Endocrinology. 154, 5, p. 623-32 10 p.

    Research output: Contribution to journal › Journal article › Research

  156. Published

    Differential effect of conditioning regimens on cytokine responses during allogeneic stem cell transplantation

    Andersen, J., Heilmann, C., Jacobsen, N., Nielsen, Claus Henrik, Bendtzen, K. & Müller, K., 1 Apr 2006, In: Bone Marrow Transplantation. 37, 7, p. 635-40 6 p.

    Research output: Contribution to journal › Journal article › Research

  157. Published

    Immunological characteristics of subjects with asymptomatic skin sensitization to birch and grass pollen

    Assing, K., Nielsen, Claus Henrik & Poulsen, Lars K., 1 Mar 2006, In: Clinical and Experimental Allergy. 36, 3, p. 283-92 10 p.

    Research output: Contribution to journal › Journal article › Research

  158. Published

    Self-reactive CD4+ T cells and B cells in the blood in health and autoimmune disease: increased frequency of thyroglobulin-reactive cells in Graves' disease

    Nielsen, Claus Henrik, Moeller, A. C., Hegedüs, L., Bendtzen, K. & Leslie, R. G. Q., 1 Mar 2006, In: Journal of Clinical Immunology. 26, 2, p. 126-37 12 p.

    Research output: Contribution to journal › Journal article › Research

  159. Published

    GABA(A) receptor function is regulated by lipid bilayer elasticity

    Søgaard, R., Werge, T. M., Bertelsen, C., Lundbye, C., Madsen, Kenneth Lindegaard, Nielsen, Claus Henrik & Lundbaek, J. A., 2006, In: Biochemistry. 45, 43, p. 13118-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  160. 2004
  161. Published

    Autoantibodies in autoimmune thyroid disease promote immune complex formation with self antigens and increase B cell and CD4+ T cell proliferation in response to self antigens

    Nielsen, Claus Henrik, Hegedüs, L. & Leslie, R. G. Q., 1 Jan 2004, In: European Journal of Immunology. 34, 1, p. 263-72 10 p.

    Research output: Contribution to journal › Journal article › Research

  162. Published

    The classical and alternative pathways of complement activation play distinct roles in spontaneous C3 fragment deposition and membrane attack complex (MAC) formation on human B lymphocytes

    Leslie, R. G. Q. & Nielsen, Claus Henrik, 1 Jan 2004, In: Immunology. 111, 1, p. 86-90 5 p.

    Research output: Contribution to journal › Journal article › Research

  163. 2003
  164. Published

    Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes

    Leslie, R. G. Q., Prodinger, W. M. & Nielsen, Claus Henrik, 1 Dec 2003, In: European Journal of Immunology. 33, 12, p. 3311-21 11 p.

    Research output: Contribution to journal › Journal article › Research

  165. 2002
  166. Published

    Complement's participation in acquired immunity

    Nielsen, Claus Henrik & Leslie, R. G. Q., 1 Aug 2002, In: Journal of Leukocyte Biology. 72, 2, p. 249-61 13 p.

    Research output: Contribution to journal › Journal article › Research

  167. Published

    The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells

    Nielsen, Claus Henrik, Pedersen, M. L., Marquart, Hanne Vibeke Hansen, Prodinger, W. M. & Leslie, R. G. Q., 1 May 2002, In: European Journal of Immunology. 32, 5, p. 1359-67 9 p.

    Research output: Contribution to journal › Journal article › Research

  168. 2001
  169. Published

    CR2-mediated activation of the complement alternative pathway results in formation of membrane attack complexes on human B lymphocytes

    Nielsen, Claus Henrik, Marquart, Hanne Vibeke Hansen, Prodinger, W. M. & Leslie, R. G., 1 Dec 2001, In: Immunology. 104, 4, p. 418-22 5 p.

    Research output: Contribution to journal › Journal article › Research

  170. Published

    Natural autoantibodies and complement promote the uptake of a self antigen, human thyroglobulin, by B cells and the proliferation of thyroglobulin-reactive CD4(+) T cells in healthy individuals

    Nielsen, Claus Henrik, Leslie, R. G., Jepsen, B. S., Kazatchkine, M. D., Kaveri, S. V. & Fischer, E., 1 Sep 2001, In: European Journal of Immunology. 31, 9, p. 2660-8 9 p.

    Research output: Contribution to journal › Journal article › Research

  171. 2000
  172. Published

    The role of complement in the acquired immune response

    Nielsen, Claus Henrik, Fischer, E. M. & Leslie, R. G., 1 May 2000, In: Immunology. 100, 1, p. 4-12 9 p.

    Research output: Contribution to journal › Journal article › Research

  173. 1998
  174. Published

    Changes in adhesion molecule expression and oxidative burst activity of granulocytes and monocytes during open-heart surgery with cardiopulmonary bypass compared with abdominal surgery

    Toft, P., Nielsen, Claus Henrik, Tønnesen, E. K., Hansen, T. G. & Hokland, M., 1 May 1998, In: European Journal of Anaesthesiology. 15, 3, p. 345-53 9 p.

    Research output: Contribution to journal › Journal article › Research

  175. Published

    Diminished ability of erythrocytes from patients with systemic lupus erythematosus to limit opsonized immune complex deposition on leukocytes and activation of granulocytes

    Nielsen, Claus Henrik, Rasmussen, J. M., Voss, A., Junker, P. & Leslie, R. G., 1 Apr 1998, In: Arthritis & Rheumatism. 41, 4, p. 613-22 10 p.

    Research output: Contribution to journal › Journal article › Research

  176. 1997
  177. Published

    The roles of complement receptors type 1 (CR1, CD35) and type 3 (CR3, CD11b/CD18) in the regulation of the immune complex-elicited respiratory burst of polymorphonuclear leukocytes in whole blood

    Nielsen, Claus Henrik, Antonsen, S., Matthiesen, S. H. & Leslie, R. G., 1 Nov 1997, In: European Journal of Immunology. 27, 11, p. 2914-9 6 p.

    Research output: Contribution to journal › Journal article › Research

  178. Published

    Effect of methylprednisolone on the oxidative burst activity, adhesion molecules and clinical outcome following open heart surgery

    Toft, P., Christiansen, K., Tønnesen, E. K., Nielsen, Claus Henrik & Lillevang, S., 1 Jan 1997, In: Scandinavian Cardiovascular Journal. 31, 5, p. 283-8 6 p.

    Research output: Contribution to journal › Journal article › Research

  179. Published

    Expression of adhesion and activation molecules on lymphocytes during open-heart surgery with cardiopulmonary bypass

    Toft, P., Tønnesen, E. K., Zülow, I., Nielsen, Claus Henrik & Hokland, M., 1 Jan 1997, In: Scandinavian Cardiovascular Journal. 31, 2, p. 91-5 5 p.

    Research output: Contribution to journal › Journal article › Research

  180. Published

    The role of complement receptor type 1 (CR1, CD35) in determining the cellular distribution of opsonized immune complexes between whole blood cells: kinetic analysis of the buffering capacity of erythrocytes

    Nielsen, Claus Henrik, Matthiesen, S. H., Lyng, I. & Leslie, R. G., 1 Jan 1997, In: Immunology. 90, 1, p. 129-37 9 p.

    Research output: Contribution to journal › Journal article › Research

  181. 1995
  182. Published

    Complement receptor expression and activation of the complement cascade on B lymphocytes from patients with systemic lupus erythematosus (SLE)

    Marquart, Hanne Vibeke Hansen, Svendsen, A., Rasmussen, J. M., Nielsen, Claus Henrik, Junker, P., Svehag, S. E. & Leslie, R. G., 1 Jul 1995, In: Clinical and Experimental Immunology. 101, 1, p. 60-5 6 p.

    Research output: Contribution to journal › Journal article › Research

  183. 1994
  184. Published

    The redistribution of granulocytes following E. coli endotoxin induced sepsis

    Toft, P., Lillevang, S. T., Tønnesen, E. K., Nielsen, Claus Henrik & Rasmussen, J. W., 1 Nov 1994, In: Acta Anaesthesiologica Scandinavica. 38, 8, p. 852-7 6 p.

    Research output: Contribution to journal › Journal article › Research

  185. Published

    Interactions of opsonized immune complexes with whole blood cells: binding to erythrocytes restricts complex uptake by leucocyte populations

    Nielsen, Claus Henrik, Svehag, S. E., Marquart, Hanne Vibeke Hansen & Leslie, R. G., 1 Aug 1994, In: Scandinavian Journal of Immunology. 40, 2, p. 228-36 9 p.

    Research output: Contribution to journal › Journal article › Research

  186. 1993
  187. Published

    Changes in blood levels of proteinase inhibitors, pregnancy zone protein, steroid carriers and complement factors induced by oral contraceptives

    Nielsen, Claus Henrik, Poulsen, H. K., Teisner, B., Thorsen, P., Hau, J. & Westergaard, J. G., 1 Sep 1993, In: European Journal of Obstetrics & Gynecology and Reproductive Biology. 51, 1, p. 63-71 9 p.

    Research output: Contribution to journal › Journal article › Research

ID: 927479