Bacterial adherence in otitis media: Determination of N-acetylgalactosamine (GalNAc) residues in the submucosal glands and surface epithelium of the normal and diseased Eustachian tube
Research output: Contribution to journal › Journal article › Research › peer-review
Acute otitis media (AOM) is the most common childhood infection caused by bacteria. The pathogenesis of AOM implicates initial adherence of a pathogen to the nasopharyngeal epithelium, which is followed by bacterial colonization of the middle ear cavity through the Eustachian tube. N-acetylgalactosamine (GalNAc) is an important constituent of mucins and GalNAc containing sugar residues seem to be essential for initial adherence of respiratory bacteria to the surface of epithelial cells.
Original language | English |
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Journal | Microbial Pathogenesis |
Volume | 51 |
Issue number | 1-2 |
Pages (from-to) | 48-57 |
Number of pages | 10 |
ISSN | 0882-4010 |
DOIs | |
Publication status | Published - Jul 2011 |
ID: 33544131