Observer variability in the histologic assessment of oral premalignant lesions

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Observer variability in the histologic assessment of oral premalignant lesions. / Karabulut, Alis; Reibel, Jesper; Therkildsen, M. H.; Prætorius, F.; Nielsen, H. W.; Dabelsteen, E.

In: Journal of Oral Pathology & Medicine, Vol. 24, No. 5, 1995, p. 198-200.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Karabulut, A, Reibel, J, Therkildsen, MH, Prætorius, F, Nielsen, HW & Dabelsteen, E 1995, 'Observer variability in the histologic assessment of oral premalignant lesions', Journal of Oral Pathology & Medicine, vol. 24, no. 5, pp. 198-200. https://doi.org/10.1111/j.1600-0714.1995.tb01166.x

APA

Karabulut, A., Reibel, J., Therkildsen, M. H., Prætorius, F., Nielsen, H. W., & Dabelsteen, E. (1995). Observer variability in the histologic assessment of oral premalignant lesions. Journal of Oral Pathology & Medicine, 24(5), 198-200. https://doi.org/10.1111/j.1600-0714.1995.tb01166.x

Vancouver

Karabulut A, Reibel J, Therkildsen MH, Prætorius F, Nielsen HW, Dabelsteen E. Observer variability in the histologic assessment of oral premalignant lesions. Journal of Oral Pathology & Medicine. 1995;24(5):198-200. https://doi.org/10.1111/j.1600-0714.1995.tb01166.x

Author

Karabulut, Alis ; Reibel, Jesper ; Therkildsen, M. H. ; Prætorius, F. ; Nielsen, H. W. ; Dabelsteen, E. / Observer variability in the histologic assessment of oral premalignant lesions. In: Journal of Oral Pathology & Medicine. 1995 ; Vol. 24, No. 5. pp. 198-200.

Bibtex

@article{cae0c48074cc11dbbee902004c4f4f50,
title = "Observer variability in the histologic assessment of oral premalignant lesions",
abstract = "Histopathologic examination of oral leukoplakias has a major impact on the assessment of prognosis and treatment planning. We investigated the extent of agreement in grading epithelial dysplasia between pathologists with the same or different educational backgrounds. Two general pathologists and two oral pathologists were each given 100 sections of oral leukoplakia to grade from no dysplasia to carcinoma in-situ. The interobserver agreement rates were in the range of 49% to 69%. The calculated kappa values were in the range of 27% to 45%, showing poor to moderate agreement between the pathologists. When comparing the kappa values between the two pairs of pathologists with the same education, these values did not diverge from the general level of kappa values, indicating that the interobserver variability was due to individual differences rather than to educational background.",
author = "Alis Karabulut and Jesper Reibel and Therkildsen, {M. H.} and F. Pr{\ae}torius and Nielsen, {H. W.} and E. Dabelsteen",
year = "1995",
doi = "10.1111/j.1600-0714.1995.tb01166.x",
language = "English",
volume = "24",
pages = "198--200",
journal = "Journal of Oral Pathology and Medicine",
issn = "0904-2512",
publisher = "Wiley-Blackwell",
number = "5",

}

RIS

TY - JOUR

T1 - Observer variability in the histologic assessment of oral premalignant lesions

AU - Karabulut, Alis

AU - Reibel, Jesper

AU - Therkildsen, M. H.

AU - Prætorius, F.

AU - Nielsen, H. W.

AU - Dabelsteen, E.

PY - 1995

Y1 - 1995

N2 - Histopathologic examination of oral leukoplakias has a major impact on the assessment of prognosis and treatment planning. We investigated the extent of agreement in grading epithelial dysplasia between pathologists with the same or different educational backgrounds. Two general pathologists and two oral pathologists were each given 100 sections of oral leukoplakia to grade from no dysplasia to carcinoma in-situ. The interobserver agreement rates were in the range of 49% to 69%. The calculated kappa values were in the range of 27% to 45%, showing poor to moderate agreement between the pathologists. When comparing the kappa values between the two pairs of pathologists with the same education, these values did not diverge from the general level of kappa values, indicating that the interobserver variability was due to individual differences rather than to educational background.

AB - Histopathologic examination of oral leukoplakias has a major impact on the assessment of prognosis and treatment planning. We investigated the extent of agreement in grading epithelial dysplasia between pathologists with the same or different educational backgrounds. Two general pathologists and two oral pathologists were each given 100 sections of oral leukoplakia to grade from no dysplasia to carcinoma in-situ. The interobserver agreement rates were in the range of 49% to 69%. The calculated kappa values were in the range of 27% to 45%, showing poor to moderate agreement between the pathologists. When comparing the kappa values between the two pairs of pathologists with the same education, these values did not diverge from the general level of kappa values, indicating that the interobserver variability was due to individual differences rather than to educational background.

U2 - 10.1111/j.1600-0714.1995.tb01166.x

DO - 10.1111/j.1600-0714.1995.tb01166.x

M3 - Journal article

VL - 24

SP - 198

EP - 200

JO - Journal of Oral Pathology and Medicine

JF - Journal of Oral Pathology and Medicine

SN - 0904-2512

IS - 5

ER -

ID: 236834