Claus Henrik Nielsen

Claus Henrik Nielsen

Professor

ORCID: 0000-0001-7543-9016

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  1. Published

    Lactobacillus reuteri supplements do not affect salivary IgA or cytokine levels in healthy subjects: A randomized, double-blind, placebo-controlled cross-over trial

    Jørgensen, Mette Rose, Keller, M. K., Kragelund, C., Hamberg, K., Ericson, D., Nielsen, Claus Henrik & Twetman, Svante, 22 Apr 2016, In: Acta Odontologica Scandinavica. 74, 5, p. 399-404 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Pseudomonas aeruginosa Microcolonies in Coronary Thrombi from Patients with ST-Segment Elevation Myocardial Infarction

    Hansen, G. M., Midjord-Belstrøm, Daniel, Nilsson, Carl Martin Peter, Helqvist, S., Nielsen, Claus Henrik, Holmstrup, Palle, Tolker-Nielsen, Tim, Givskov, Michael & Hansen, Peter Riis, 2016, In: P L o S One. 11, 12, 13 p., e0168771.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking

    Massarenti, Laura, Enevold, C., Damgaard, D., Ødum, Niels, Garred, Peter, Frisch, M., Shelef, M. A., Jacobsen, Søren & Nielsen, Claus Henrik, 2021, In: Frontiers in Immunology. 12, 707690.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Porphyromonas gingivalis in saliva associates with chronic and aggressive periodontitis

    Damgaard, Christian, Danielsen, Anne Katrine, Enevold, C., Massarenti, Laura, Nielsen, Claus Henrik, Holmstrup, Palle & Midjord-Belstrøm, Daniel, 2019, In: Journal of Oral Microbiology. 11, 1, p. 1-9 9 p., 1653123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A matrix of cholesterol crystals, but not cholesterol alone, primes human monocytes/macrophages for excessive endotoxin-induced production of tumor necrosis factor-alpha. Role in atherosclerotic inflammation?

    Bendtzen, K., Christensen, O., Nielsen, Claus Henrik & Holmstrup, Palle, Jun 2014, In: Discovery Medicine. 17, 96, p. 309-12 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase

    Nielsen, Claus Henrik, Brix, T. H., Leslie, R. G. Q. & Hegedüs, L., 2009, In: Clinical Immunology. 133, 2, p. 218-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Absence of Bacteria on Coronary Angioplasty Balloons from Unselected Patients: Results with Use of a High Sensitivity Polymerase Chain Reaction Assay

    Hansen, G. M., Nilsson, M., Nielsen, Claus Henrik, Holmstrup, Palle, Helqvist, S., Tolker-Nielsen, Tim, Givskov, Michael & Hansen, Peter Riis, 2015, In: PloS one. 10, 12, p. 1-11 11 p., e0145657.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Activated platelets enhance IL-10 secretion and reduce TNF-α secretion by monocytes

    Gudbrandsdottir, S., Hasselbalch, H. C. & Nielsen, Claus Henrik, 15 Oct 2013, In: Journal of immunology (Baltimore, Md. : 1950). 191, 8, p. 4059-67 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients

    Bliddal, S., Banasik, Karina, Pedersen, Ole Birger Vesterager, Nissen, J., Cantwell, Lisa, Schwinn, M., Tulstrup, Morten Rytter, Westergaard, David, Ullum, H., Brunak, Søren, Tommerup, Niels, Feenstra, B., Geller, F., Ostrowski, Sisse Rye, Grønbæk, Kirsten, Nielsen, Claus Henrik, Nielsen, Susanne Dam & Feldt-Rasmussen, Ulla, 2021, In: Scientific Reports. 11, 13153.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Altered balance between self-reactive T helper (Th)17 cells and Th10 cells and between full-length forkhead box protein 3 (FoxP3) and FoxP3 splice variants in Hashimoto's thyroiditis

    Kristensen, B., Hegedüs, L., Madsen, H. O., Smith, T. J. & Nielsen, Claus Henrik, Apr 2015, In: Clinical and Experimental Immunology. 180, 1, p. 58-69 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4

    Martín Monreal, M. T., Stripp, Alexandra, Massarenti, Laura, Mondal, S., Šenolt, L., Ødum, Niels, Nielsen, Michael Lund, Thompson, P. R., Nielsen, Claus Henrik & Damgaard, D., 2021, In: Frontiers in Immunology. 12, 11 p., 716250.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Application of new therapies in Graves' disease and thyroid-associated ophthalmopathy: animal models and translation to human clinical trials

    Banga, J. P., Nielsen, Claus Henrik, Gilbert, J. A., Fassi, Daniel El & Hegedus, L., 1 Sep 2008, In: Thyroid. 18, 9, p. 973-81 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Application of new therapies in Graves' disease and thyroid-associated ophthalmopathy: animal models and translation to human clinical trialsTumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease

    Banga, J. P., Gilbert, J. A., El, F. D., Hegedus, L. & Nielsen, Claus Henrik, 2008, In: Thyroid. 18, 9, p. 973-981 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Assessment of peptidylarginine deiminase activity by ELISA using human fibrinogen as substrate

    Damgaard, D. & Nielsen, Claus Henrik, 2019, Autoantibodies: Methods and Protocols. Houen, G. (ed.). Humana Press, p. 239-242 4 p. (Methods in Molecular Biology, Vol. 1901).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Associations between serum and plasma brain-derived neurotrophic factor and influence of storage time and centrifugation strategy

    Gejl, A. K., Enevold, C., Bugge, A., Andersen, M. S., Nielsen, Claus Henrik & Andersen, L. B., 2019, In: Scientific Reports. 9, 9 p., 9655.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Autoantibodies in autoimmune thyroid disease promote immune complex formation with self antigens and increase B cell and CD4+ T cell proliferation in response to self antigens

    Nielsen, Claus Henrik, Hegedüs, L. & Leslie, R. G. Q., 1 Jan 2004, In: European Journal of Immunology. 34, 1, p. 263-72 10 p.

    Research output: Contribution to journal › Journal article › Research

  17. Published

    Autoantibodies to myelin basic protein (MBP) in healthy individuals and in patients with multiple sclerosis: a role in regulating cytokine responses to MBP

    Hedegaard, C. J., Chen, N., Sellebjerg, Finn Thorup, Sørensen, Per Soelberg, Leslie, R. G. Q., Bendtzen, K. & Nielsen, Claus Henrik, 1 Sep 2009, In: Immunology. 128, 1 Suppl, p. e451-61

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    B lymphocyte depletion with the monoclonal antibody rituximab in Graves' disease: a controlled pilot study

    Fassi, Daniel El , Nielsen, Claus Henrik, Bonnema, S. J., Hasselbalch, H. K. & Hegedüs, L., 1 May 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 5, p. 1769-72 4 p.

    Research output: Contribution to journal › Journal article › Research

  19. Published

    B-cell cytokine responses to Porphyromonas gingivalis in patients with periodontitis and healthy controls

    Danielsen, Anne Katrine, Damgaard, Christian, Massarenti, Laura, Jensen, Peter Østrup, Hansen, Peter Riis, Holmstrup, Palle & Nielsen, Claus Henrik, 2023, In: Journal of Periodontology. 94, 8, p. 997-1007 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    B-cell depletion with rituximab in the treatment of autoimmune diseases. Graves' ophthalmopathy the latest addition to an expanding family

    Nielsen, Claus Henrik, Fassi, Daniel El , Hasselbalch, H. K., Bendtzen, K. & Hegedüs, L., 1 Jul 2007, In: Expert Opinion on Biological Therapy. 7, 7, p. 1061-78 18 p.

    Research output: Contribution to journal › Journal article › Research

  21. Published

    B-lymfocytdepletring og andre biologiske behandlingsmuligheder ved Graves' oftalmopatiTumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease

    El, F. D., Hegedus, L. & Nielsen, Claus Henrik, 2008, In: Ugeskrift for læger. 170, 24, p. 2128-2130 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Bacterial profiles of saliva in relation to diet, lifestyle factors, and socioeconomic status

    Midjord-Belstrøm, Daniel, Holmstrup, Palle, Nielsen, Claus Henrik, Kirkby, N., Twetman, Svante, Heitmann, Berit, Klepac-Ceraj, V., Paster, B. J. & Fiehn, Nils-Erik, 2014, In: Journal of Oral Microbiology. 6, p. 1-9 9 p., 23609.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Benzoxazinoids: Cereal phytochemicals with putative therapeutic and health-protecting properties

    Adhikari, K. B., Tanwir, F., Gregersen, P. L., Steffensen, S. K., Jensen, B. M., Poulsen, Lars K., Nielsen, Claus Henrik, Høyer, S., Borre, M. & Fomsgaard, I. S., Jul 2015, In: Molecular Nutrition & Food Research. 59, 7, p. 1324-1338 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Biologiske behandlingsmuligheder ved Graves' oftalmopati

    Fassi, Daniel El , Nielsen, Claus Henrik & Hegedüs, L., 9 Jun 2008, In: Ugeskrift for Laeger. 170, 24, p. 2128-30 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Biomimetic triblock copolymer membrane arrays: A stable template for functional membrane proteins

    Gonzalez-Perez, Alfredo, Stibius, K. B., Vissing, T., Nielsen, Claus Henrik & Mouritsen, Ole G., 15 Sep 2009, In: Langmuir. 25, 18, p. 10447-10450 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Blood Cell Biomarkers of Inflammation and Cytokine Levels as Predictors of Response to Biologics in Patients with Psoriasis

    Andersen, C. S. B., Kvist-Hansen, A., Siewertsen, M., Enevold, C., Hansen, Peter Riis, Knudsen, Diljit Kaur, Zachariae, Claus, Nielsen, Claus Henrik, Loft, N. & Skov, Lone, 2023, In: International Journal of Molecular Sciences. 24, 7, 15 p., 6111.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    CDX2 regulates interleukin-33 gene expression in intestinal epithelial cells (LS174T)

    Larsen, S., Seidelin, Jakob Benedict, Davidsen, J., Dahlgaard, K., Nielsen, Claus Henrik, Bennett, Eric Paul, Pedersen, O. B., Coskun, M. & Troelsen, J. T., 2021, In: FEBS Open Bio. 11, 6, p. 1638-1644

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    CR2-mediated activation of the complement alternative pathway results in formation of membrane attack complexes on human B lymphocytes

    Nielsen, Claus Henrik, Marquart, Hanne Vibeke Hansen, Prodinger, W. M. & Leslie, R. G., 1 Dec 2001, In: Immunology. 104, 4, p. 418-22 5 p.

    Research output: Contribution to journal › Journal article › Research

  29. Published

    Cell saver for on-pump coronary operations reduces systemic inflammatory markers: a randomized trial

    Damgaard, Sune, Nielsen, Claus Henrik, Andersen, L. W., Bendtzen, K., Tvede, M. & Steinbrüchel, D., 1 May 2010, In: Annals of Thoracic Surgery. 89, 5, p. 1511-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Cerebral abscesses with odontogenic origin: a population-based cohort study

    Jespersen, Frederik Viktor Bang, Hansen, S. U., Jensen, Simon Storgård, Omland, L. H., Helweg-Larsen, J., Bjarnsholt, Thomas, Nielsen, Claus Henrik, Ziebell, M., Bodilsen, J. & Markvart, Merete, 2023, In: Clinical Oral Investigations. 27, 7, p. 3639-364

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Changes in adhesion molecule expression and oxidative burst activity of granulocytes and monocytes during open-heart surgery with cardiopulmonary bypass compared with abdominal surgery

    Toft, P., Nielsen, Claus Henrik, Tønnesen, E. K., Hansen, T. G. & Hokland, M., 1 May 1998, In: European Journal of Anaesthesiology. 15, 3, p. 345-53 9 p.

    Research output: Contribution to journal › Journal article › Research

  32. Published

    Changes in blood levels of proteinase inhibitors, pregnancy zone protein, steroid carriers and complement factors induced by oral contraceptives

    Nielsen, Claus Henrik, Poulsen, H. K., Teisner, B., Thorsen, P., Hau, J. & Westergaard, J. G., 1 Sep 1993, In: European Journal of Obstetrics & Gynecology and Reproductive Biology. 51, 1, p. 63-71 9 p.

    Research output: Contribution to journal › Journal article › Research

  33. Published

    Characterization of circulating extracellular traps and immune responses to citrullinated LL37 in psoriasis

    Monreal, M. T. M., Kvist-Hansen, A., Massarenti, Laura, Steffensen, R., Loft, N., Hansen, Peter Riis, Ødum, Niels, Skov, Lone & Nielsen, Claus Henrik, 2023, In: Frontiers in Immunology. 14, 10 p., 1247592.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Characterization of patients with odontogenic necrotizing soft tissue infections in the head and neck area: A retrospective analysis

    Hansen, S. U., Jespersen, Frederik Viktor Bang, Markvart, Merete, Hyldegaard, Ole, Plaschke, Christina Caroline, Bjarnsholt, Thomas, Nielsen, Claus Henrik & Jensen, Simon Storgård, 2023, In: Acta Odontologica Scandinavica. 82, 1, p. 40-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Cholesterol crystals enhance TLR2-and TLR4-mediated pro-inflammatory cytokine responses of monocytes to the proatherogenic oral bacterium Porphyromonas gingivalis

    Køllgaard, T. M. S., Enevold, Christian, Bendtzen, K., Hansen, Peter Riis, Givskov, Michael, Holmstrup, Palle & Nielsen, Claus Henrik, 24 Feb 2017, In: P L o S One. 12, 2, 14 p., 0172773.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Circulating antibodies against leukotoxin A as marker of periodontitis grades B and C and oral infection with Aggregatibacter actinomycetemcomitans

    Damgaard, Christian, Danielsen, Anne Katrine, Enevold, C., Reinholdt, J., Holmstrup, Palle, Nielsen, Claus Henrik & Massarenti, Laura, 2021, In: Journal of Periodontology. 92, 12, p. 1795-1804 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Citrullination of myelin basic protein induces a Th17-cell response in healthy individuals and enhances the presentation of MBP85-99 in patients with multiple sclerosis

    Martín Monreal, M. T., Hansen, B. E., Iversen, P. F., Enevold, Christian, Ødum, Niels, Sellebjerg, Finn Thorup, Højrup, P., von Essen, Marina Rode & Nielsen, Claus Henrik, 2023, In: Journal of Autoimmunity. 139, 103092.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Class switch recombination in selective IgA-deficient subjects

    Jensen, L. H., Ryder, L. P., Nielsen, L. K., Nielsen, Claus Henrik & Poulsen, Lars K., 1 Jun 2006, In: Clinical and Experimental Immunology. 144, 3, p. 458-66 9 p.

    Research output: Contribution to journal › Journal article › Research

  39. Published

    Comorbidity of periodontal disease: two sides of the same coin? An introduction for the clinician

    Holmstrup, Palle, Damgaard, Christian, Olsen, I., Klinge, B., Flyvbjerg, A., Nielsen, Claus Henrik & Hansen, Peter Riis, 2017, In: Journal of Oral Microbiology. 9, 1, 14 p., 1332710.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Complement component 3 and its activation split-products in saliva associate with periodontitis

    Damgaard, Christian, Massarenti, Laura, Danielsen, Anne Katrine, Graversen, J. H., Holmstrup, Palle, Nielsen, Claus Henrik & Palarasah, Y., 2022, In: Journal of Periodontology. 93, 9, p. 1294-1301 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Complement receptor expression and activation of the complement cascade on B lymphocytes from patients with systemic lupus erythematosus (SLE)

    Marquart, Hanne Vibeke Hansen, Svendsen, A., Rasmussen, J. M., Nielsen, Claus Henrik, Junker, P., Svehag, S. E. & Leslie, R. G., 1 Jul 1995, In: Clinical and Experimental Immunology. 101, 1, p. 60-5 6 p.

    Research output: Contribution to journal › Journal article › Research

  42. Published

    Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes

    Leslie, R. G. Q., Prodinger, W. M. & Nielsen, Claus Henrik, 1 Dec 2003, In: European Journal of Immunology. 33, 12, p. 3311-21 11 p.

    Research output: Contribution to journal › Journal article › Research

  43. Published

    Complement split product C3c in saliva as biomarker for periodontitis and response to periodontal treatment

    Suell, Maria Grande, Midjord-Belstrøm, Daniel, Damgaard, Christian, Holmstrup, Palle, Thangaraj, S. S., Nielsen, Claus Henrik & Palarasah, Y., 2021, In: Journal of Periodontal Research. 56, 1, p. 27-33 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Complement's participation in acquired immunity

    Nielsen, Claus Henrik & Leslie, R. G. Q., 1 Aug 2002, In: Journal of Leukocyte Biology. 72, 2, p. 249-61 13 p.

    Research output: Contribution to journal › Journal article › Research

  45. Published

    Decreased interleukin-2 responses to Fusobacterium nucleatum and Porphyromonas gingivalis in generalized aggressive periodontitis

    Borch, T. S., Løbner, M., Bendtzen, K., Holmstrup, Palle & Nielsen, Claus Henrik, 2009, In: Journal of Periodontology. 80, 5, p. 800-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Demonstration of extracellular peptidylarginine deiminase (PAD) activity in synovial fluid of patients with rheumatoid arthritis using a novel assay for citrullination of fibrinogen

    Damgaard, D., Senolt, L., Nielsen, M. F., Pruijn, G. J. & Nielsen, Claus Henrik, 2014, In: Arthritis Research & Therapy (Print). 16, 6, p. 1-7 7 p., 498.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Dietary exposure to benzoxazinoids enhances bacteria-induced monokine responses by peripheral blood mononuclear cells

    Damgaard, D., Jensen, B. M., Palarasah, Y., Nielsen, M. F. B., Adhikari, K. B., Schnoor, H. J., Juel-Berg, N., Poulsen, Lars K., Fomsgaard, I. S. & Nielsen, Claus Henrik, Nov 2015, In: Molecular Nutrition & Food Research (Online). 59, 11, p. 2190-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Differences in bacterial saliva profile between periodontitis patients and a control cohort

    Midjord-Belstrøm, Daniel, Fiehn, Nils-Erik, Nielsen, Claus Henrik, Kirkby, N., Twetman, Svante, Klepac-Ceraj, V., Paster, B. J. & Holmstrup, Palle, Feb 2014, In: Journal of Clinical Periodontology. 41, 2, p. 104-12 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Differential effect of conditioning regimens on cytokine responses during allogeneic stem cell transplantation

    Andersen, J., Heilmann, C., Jacobsen, N., Nielsen, Claus Henrik, Bendtzen, K. & Müller, K., 1 Apr 2006, In: Bone Marrow Transplantation. 37, 7, p. 635-40 6 p.

    Research output: Contribution to journal › Journal article › Research

  50. Published

    Differentiation of salivary bacterial profiles of subjects with periodontitis and dental caries

    Midjord-Belstrøm, Daniel, Fiehn, Nils-Erik, Nielsen, Claus Henrik, Klepac-Ceraj, V., Paster, B. J., Twetman, Svante & Holmstrup, Palle, 2015, In: Journal of Oral Microbiology. 7, p. 1-5 5 p., 27429.

    Research output: Contribution to journal › Journal article › Research › peer-review

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