Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions?

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions? / Kragelund, Camilla; Hansen, Claus; Reibel, Jesper; Nauntofte, Birgitte; Brøsen, Kim; Jensen, Siri Beier; Torpet, Lis Andersen.

In: Journal of Oral Pathology & Medicine, Vol. 39, No. 6, 07.2010, p. 497-505.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Kragelund, C, Hansen, C, Reibel, J, Nauntofte, B, Brøsen, K, Jensen, SB & Torpet, LA 2010, 'Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions?', Journal of Oral Pathology & Medicine, vol. 39, no. 6, pp. 497-505. https://doi.org/10.1111/j.1600-0714.2010.00897.x

APA

Kragelund, C., Hansen, C., Reibel, J., Nauntofte, B., Brøsen, K., Jensen, S. B., & Torpet, L. A. (2010). Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions? Journal of Oral Pathology & Medicine, 39(6), 497-505. https://doi.org/10.1111/j.1600-0714.2010.00897.x

Vancouver

Kragelund C, Hansen C, Reibel J, Nauntofte B, Brøsen K, Jensen SB et al. Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions? Journal of Oral Pathology & Medicine. 2010 Jul;39(6):497-505. https://doi.org/10.1111/j.1600-0714.2010.00897.x

Author

Kragelund, Camilla ; Hansen, Claus ; Reibel, Jesper ; Nauntofte, Birgitte ; Brøsen, Kim ; Jensen, Siri Beier ; Torpet, Lis Andersen. / Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions?. In: Journal of Oral Pathology & Medicine. 2010 ; Vol. 39, No. 6. pp. 497-505.

Bibtex

@article{a22a26a0aab811df928f000ea68e967b,
title = "Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions?",
abstract = "Lichenoid drug eruptions (LDE) in the oral cavity are adverse drug reactions (ADR) that are impossible to differentiate from oral lichen planus (OLP) as no phenotypic criteria exist. Impaired function of polymorphic cytochrome 450-enzymes (CYPs) may cause increased plasma concentration of some drugs resulting in ADR/LDE. In an earlier study we did not find more patients with OLP (OLPs) with impaired CYP-genotype.",
keywords = "Adult, Aged, Aged, 80 and over, Alleles, Aryl Hydrocarbon Hydroxylases, Chi-Square Distribution, Cytochrome P-450 CYP2D6, Diagnosis, Differential, Drug Interactions, Female, Genotype, Humans, Lichen Planus, Oral, Male, Mephenytoin, Middle Aged, Phenotype, Polymorphism, Genetic, Polypharmacy, Questionnaires, Sparteine, Statistics, Nonparametric",
author = "Camilla Kragelund and Claus Hansen and Jesper Reibel and Birgitte Nauntofte and Kim Br{\o}sen and Jensen, {Siri Beier} and Torpet, {Lis Andersen}",
note = "Paper id:: 20492431",
year = "2010",
month = jul,
doi = "10.1111/j.1600-0714.2010.00897.x",
language = "English",
volume = "39",
pages = "497--505",
journal = "Journal of Oral Pathology and Medicine",
issn = "0904-2512",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Can the genotype or phenotype of two polymorphic drug metabolising cytochrome P450-enzymes identify oral lichenoid drug eruptions?

AU - Kragelund, Camilla

AU - Hansen, Claus

AU - Reibel, Jesper

AU - Nauntofte, Birgitte

AU - Brøsen, Kim

AU - Jensen, Siri Beier

AU - Torpet, Lis Andersen

N1 - Paper id:: 20492431

PY - 2010/7

Y1 - 2010/7

N2 - Lichenoid drug eruptions (LDE) in the oral cavity are adverse drug reactions (ADR) that are impossible to differentiate from oral lichen planus (OLP) as no phenotypic criteria exist. Impaired function of polymorphic cytochrome 450-enzymes (CYPs) may cause increased plasma concentration of some drugs resulting in ADR/LDE. In an earlier study we did not find more patients with OLP (OLPs) with impaired CYP-genotype.

AB - Lichenoid drug eruptions (LDE) in the oral cavity are adverse drug reactions (ADR) that are impossible to differentiate from oral lichen planus (OLP) as no phenotypic criteria exist. Impaired function of polymorphic cytochrome 450-enzymes (CYPs) may cause increased plasma concentration of some drugs resulting in ADR/LDE. In an earlier study we did not find more patients with OLP (OLPs) with impaired CYP-genotype.

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Alleles

KW - Aryl Hydrocarbon Hydroxylases

KW - Chi-Square Distribution

KW - Cytochrome P-450 CYP2D6

KW - Diagnosis, Differential

KW - Drug Interactions

KW - Female

KW - Genotype

KW - Humans

KW - Lichen Planus, Oral

KW - Male

KW - Mephenytoin

KW - Middle Aged

KW - Phenotype

KW - Polymorphism, Genetic

KW - Polypharmacy

KW - Questionnaires

KW - Sparteine

KW - Statistics, Nonparametric

U2 - 10.1111/j.1600-0714.2010.00897.x

DO - 10.1111/j.1600-0714.2010.00897.x

M3 - Journal article

C2 - 20492431

VL - 39

SP - 497

EP - 505

JO - Journal of Oral Pathology and Medicine

JF - Journal of Oral Pathology and Medicine

SN - 0904-2512

IS - 6

ER -

ID: 21454348