Claus Henrik Nielsen

Claus Henrik Nielsen

Professor

ORCID: 0000-0001-7543-9016

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  1. Published

    Periodontitis increases risk of viable bacteria in freshly drawn blood donations

    Damgaard, Christian, Sækmose, S. G., Nilsson, Carl Martin Peter, Kilian, Mogens, Nielsen, Claus Henrik & Holmstrup, Palle, 2021, In: Blood Transfusion. 19, 5, p. 376-383

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Phthalates Are Metabolised by Primary Thyroid Cell Cultures but Have Limited Influence on Selected Thyroid Cell Functions In Vitro

    Hansen, J. F., Brorson, M. M., Boas, M., Frederiksen, H., Nielsen, Claus Henrik, Lindström, E. S., Hofman-Bang, J., Hartoft-Nielsen, M., Frisch, T., Main, Katharina Maria, Bendtzen, K., Rasmussen, Å. K. & Feldt-Rasmussen, Ulla, 2016, In: P L o S One. 11, 3, 16 p., e0151192.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Porphyromonas gingivalis-induced production of reactive oxygen species, tumor necrosis factor-α, interleukin-6, CXCL8 and CCL2 by neutrophils from localized aggressive periodontitis and healthy donors: modulating actions of red blood cells and resolvin E1

    Damgaard, Christian, Kantarci, A., Holmstrup, Palle, Hasturk, H., Nielsen, Claus Henrik & Van Dyke, T. E., 2017, In: Journal of Periodontal Research. 52, 2, p. 246-254 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Preoperative methylprednisolone enhances recovery after endovascular aortic repair: a randomized, double-blind, placebo-controlled clinical trial

    de la Motte, L., Kehlet, Henrik, Vogt, K., Nielsen, Claus Henrik, Groenvall, J. B., Nielsen, H. B., Andersen, A., Schroeder, T. V. & Lönn, Lars, Sep 2014, In: Annals of Surgery. 260, 3, p. 540-549

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Production of interleukin (IL)-5 and IL-10 accompanies T helper cell type 1 (Th1) cytokine responses to a major thyroid self-antigen, thyroglobulin, in health and autoimmune thyroid disease

    Nielsen, Claus Henrik, Hegedüs, L., Rieneck, K., Moeller, A. C., Leslie, R. G. Q. & Bendtzen, K., 1 Feb 2007, In: Clinical and Experimental Immunology. 147, 2, p. 287-95 9 p.

    Research output: Contribution to journal › Journal article › Research

  6. Published

    Prognostic role of genetic polymorphisms of the interleukin-6 signaling pathway in patients with severe heart failure

    Hansen, Peter Riis, Nelveg-Kristensen, K. E., Rasmussen, H. B., Torp-Pedersen, C., Køber, Lars Valeur, Nielsen, Claus Henrik & Enevold, C., 2019, In: Pharmacogenomics Journal. 19, p. 428-437

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Rapid eye movement-sleep is reduced in patients with acute uncomplicated diverticulitis—an observational study

    Huang, C., Alamili, M., Nielsen, Claus Henrik, Rosenberg, Jacob & Gögenur, I., 2015, In: PeerJ. 3, p. 1-13 13 p., 1146.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase

    Damgaard, D., Bjørn, M. E., Jensen, Peter Østrup & Nielsen, Claus Henrik, Dec 2017, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 32, 1, p. 1203-1208 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Recent advances in understanding autoimmune thyroid disease: the tallest tree in the forest of polyautoimmunity

    Bliddal, S., Nielsen, Claus Henrik & Feldt-Rasmussen, Ulla, 2017, In: F1000Research. 6, 12 p., 1776.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Reconstitution of Th17, Tc17 and Treg cells after paediatric haematopoietic stem cell transplantation: Impact of interleukin-7

    Kielsen, K., Ryder, L. P., Lennox-Hvenekilde, D., Gad, M., Nielsen, Claus Henrik, Heilmann, C., Ifversen, M., Pedersen, Anders Elm & Muller, Klaus, Feb 2018, In: Immunobiology. 223, 2, p. 220-226 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Reduced folate carrier polymorphism determines methotrexate uptake by B cells and CD4+ T cells

    Baslund, B., Gregers, J. & Nielsen, Claus Henrik, 1 Apr 2008, In: Rheumatology. 47, 4, p. 451-3 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Reduced folate carrier polymorphism determines methotrexate uptake by B cells and CD4+ T cellsTumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease

    Baslund, B., Gregers, J. & Nielsen, Claus Henrik, 2008, In: Rheumatology.(Oxford). 47, 4, p. 451-453 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Reduced glutathione as a physiological co-activator in the activation of peptidylarginine deiminase

    Damgaard, D., Bjørn, M. E., Steffensen, Maria Abildgaard, Pruijn, G. J. M. & Nielsen, Claus Henrik, 5 May 2016, In: Arthritis Research & Therapy. 18, 1, p. 102 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3

    Damgaard, D., Bawadekar, M., Senolt, L., Stensballe, A., Shelef, M. A. & Nielsen, Claus Henrik, 2018, In: PLoS ONE. 13, 8, p. 1-14 e0203214.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Release of active peptidylarginine deiminase into the circulation during acute inflammation induced by coronary artery bypass surgery

    Vejlstrup, A., Møller, A. M., Nielsen, Claus Henrik & Damgaard, D., 2019, In: Journal of Inflammation Research. 12, p. 137-144

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Rituximab (MabThera) til behandling af aktiv reumatoid artritis

    Fassi, Daniel El , Nielsen, Claus Henrik & Bendtzen, K., 20 Nov 2006, In: Ugeskrift for Laeger. 168, 47, p. 4079-81 3 p.

    Research output: Contribution to journal › Journal article › Research

  17. Published

    Rituximab and dexamethasone vs dexamethasone monotherapy in newly diagnosed patients with primary immune thrombocytopenia

    Gudbrandsdottir, S., Birgens, H. S., Frederiksen, H., Jensen, B. A., Jensen, M. K., Kjeldsen, L., Klausen, T. W., Larsen, H., Mourits-Andersen, H. T., Nielsen, Claus Henrik, Nielsen, O. J., Plesner, T., Pulczynski, S., Rasmussen, I. H., Rønnov-Jessen, D. & Hasselbalch, H. C., 14 Mar 2013, In: Blood. 121, 11, p. 1976-81 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Ruxolitinib and interferon-alpha 2 combination therapy for patients with polycythemia vera or myelofibrosis: a phase II study

    Sorensen, A. L., Mikkelsen, Stine Ulrik, Knudsen, T. A., Bjorn, M. E., Andersen, Christen Bertel L, Bjerrum, O. W., Brochmann, N., Patel, D. A., Gjerdrum, Lise Mette Rahbek, El Fassi, D., Kruse, T. A., Larsen, T. S., Mourits-Andersen, H. T., Nielsen, Claus Henrik, Ellervik, Christina, Pallisgaard, N., Thomassen, M., Kjaer, L., Skov, V. & Hasselbach, H. C., 2020, In: Haematologica. 105, 9, p. 2262-2272 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Ruxolitinib treatment reduces monocytic superoxide radical formation without affecting hydrogen peroxide formation or systemic oxidative nucleoside damage in myelofibrosis

    Bjørn, M. E., Brimnes, M. K., Gudbrandsdottir, S., Andersen, C. L., Poulsen, Henrik Enghusen, Henriksen, T., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, Oct 2019, In: Leukemia and Lymphoma. 60, 10, p. 2549-2557 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Safety and efficacy of combination therapy of interferon-α2 and ruxolitinib in polycythemia vera and myelofibrosis

    Mikkelsen, Stine Ulrik, Kjaer, L., Bjørn, M. E., Knudsen, T. A., Sørensen, A. L., Andersen, Christen Bertel L, Bjerrum, O. W., Brochmann, N., Fassi, Daniel El , Kruse, T. A., Larsen, T. S., Mourits-Andersen, H. T., Nielsen, Claus Henrik, Pallisgaard, N., Thomassen, M., Skov, V. & Hasselbalch, Hans Carl, Aug 2018, In: Cancer Medicine. 7, 8, p. 3571-3581 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Self-reactive CD4+ T cells and B cells in the blood in health and autoimmune disease: increased frequency of thyroglobulin-reactive cells in Graves' disease

    Nielsen, Claus Henrik, Moeller, A. C., Hegedüs, L., Bendtzen, K. & Leslie, R. G. Q., 1 Mar 2006, In: Journal of Clinical Immunology. 26, 2, p. 126-37 12 p.

    Research output: Contribution to journal › Journal article › Research

  22. Published

    Severe weight loss in a hypothyroid patient as an acute presentation of autoimmune polyglandular syndrome type II

    Silajdzija, E., Bliddal, S., Borgwardt, L., Rossing, M., Jarløv, A., Nielsen, Claus Henrik & Feldt-Rasmussen, Ulla, 2022, In: Hormones. 21, 2, p. 317-322

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Single nucleotide polymorphisms in genes encoding toll-like receptors 7, 8 and 9 in Danish patients with systemic lupus erythematosus

    Enevold, Christian, Nielsen, Claus Henrik, Jacobsen, R. S., Hermansen, M. F., Molbo, Drude, Avlund, K., Bendtzen, K. & Jacobsen, Søren, 2014, In: Molecular Biology Reports. 41, 9, p. 5755-5763 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Sjögren's syndrome: novel insights from proteomics and miRNA expression analysis

    Kamounah, Sarah, Sembler-Møller, Maria Lynn, Nielsen, Claus Henrik & Pedersen, Anne Marie Lynge, 2023, In: Frontiers in Immunology. 14, 21 p., 1183195.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Smoking is associated with increased levels of extracellular peptidylarginine deiminase 2 (PAD2) in the lungs

    Damgaard, D., Friberg Bruun Nielsen, M., Quisgaard Gaunsbaek, M., Palarasah, Y., Svane-Knudsen, V. & Nielsen, Claus Henrik, 2015, In: Clinical and Experimental Rheumatology. 33, 3, p. 405-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Spontaneous complement activation on human B cells results in localized membrane depolarization and the clustering of complement receptor type 2 and C3 fragments

    Løbner, M., Leslie, R. G. Q., Prodinger, W. M. & Nielsen, Claus Henrik, 2009, In: Immunology. 128, 1 Suppl, p. e661-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. E-pub ahead of print

    Suitability of machine learning models for prediction of clinically defined Stage III/IV periodontitis from questionnaires and demographic data in Danish cohorts

    Enevold, Christian, Nielsen, Claus Henrik, Christensen, Lisa Bøge, Kongstad, Johanne, Fiehn, Nils-Erik, Hansen, Peter Riis, Holmstrup, Palle, Havemose-Poulsen, A. & Damgaard, Christian, 2024, (E-pub ahead of print) In: Journal of Clinical Periodontology. 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Surfactant Protein D Deficiency Aggravates Cigarette Smoke-Induced Lung Inflammation by Upregulation of Ceramide Synthesis

    Pilecki, B., Wulf-Johansson, H., Støttrup, C., Jørgensen, P. T., Djiadeu, P., Nexøe, A. B., Schlosser, A., Hansen, S. W. K., Madsen, J., Clark, H. W., Nielsen, Claus Henrik, Vestbo, J., Palaniyar, N., Holmskov, U. & Sorensen, G. L., 2018, In: Frontiers in Immunology. 9, 12 p., 3013.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Surfactant protein D is proatherogenic in mice

    Sorensen, G. L., Madsen, J., Kejling, K., Tornoe, I., Nielsen, O., Townsend, P., Poulain, F., Nielsen, Claus Henrik, Reid, K. B. M., Hawgood, S., Falk, E. & Holmskov, U., 1 Jun 2006, In: American Journal of Physiology: Heart and Circulatory Physiology. 290, 6, p. H2286-94

    Research output: Contribution to journal › Journal article › Research

  30. Published

    Systemic adverse events following rituximab therapy in patients with Graves' disease

    Fassi, Daniel El , Nielsen, Claus Henrik, Junker, M. P., Hasselbalch, H. C. & Hegedüs, L., 2011, In: Journal of Endocrinological Investigation. 34, 7, p. e163-7

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

    Hedegaard, C. J., Krakauer, M., Bendtzen, K., Lund, H., Sellebjerg, Finn Thorup & Nielsen, Claus Henrik, 1 Oct 2008, In: Immunology. 125, 2, p. 161-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Targeted biological therapies for Graves' disease and thyroid-associated ophthalmopathy. Focus on B-cell depletion with Rituximab

    Hegedüs, L., Smith, T. J., Douglas, R. S., Nielsen, Claus Henrik & Smith, T. J., 1 Jan 2011, In: Clinical Endocrinology. 74, 1, p. 1-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Telomerase Inhibitor Imetelstat in Essential Thrombocythemia and Myelofibrosis

    Bjørn, M. E., Nielsen, Claus Henrik & Hasselbalch, H. C., 24 Dec 2015, In: New England Journal of Medicine. 373, 26, p. 2579-80 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  34. Published

    The Extracellular Polysaccharide Matrix of Pseudomonas aeruginosa Biofilms Is a Determinant of Polymorphonuclear Leukocyte Responses

    Rybtke, Morten Levin, Jensen, Peter Østrup, Nielsen, Claus Henrik & Tolker-Nielsen, Tim, 2021, In: Infection and Immunity. 89, 1

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The HLA-DP2 protein binds the immunodominant epitope from myelin basic protein, MBP85-99, with high affinity

    Hansen, B. E., Nielsen, Claus Henrik, Madsen, H. O., Ryder, L. P., Jakobsen, B. K. & Svejgaard, A., 1 Mar 2011, In: HLA. 77, 3, p. 229-34 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The atherogenic bacterium Porphyromonas gingivalis evades circulating phagocytes by adhering to erythrocytes

    Midjord-Belstrøm, Daniel, Holmstrup, Palle, Damgaard, Christian, Borch, T. S., Skjødt, M., Bendtzen, K. & Nielsen, Claus Henrik, 1 Apr 2011, In: Infection and Immunity. 79, 4, p. 1559-65 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The cellular cancer resistance of the SR/CR mouse

    Koch, J., Hau, Jann, Jensen, Henrik Elvang, Nielsen, Claus Henrik & Rieneck, K., 2012, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 120, 12, p. 974-987 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The classical and alternative pathways of complement activation play distinct roles in spontaneous C3 fragment deposition and membrane attack complex (MAC) formation on human B lymphocytes

    Leslie, R. G. Q. & Nielsen, Claus Henrik, 1 Jan 2004, In: Immunology. 111, 1, p. 86-90 5 p.

    Research output: Contribution to journal › Journal article › Research

  39. Published

    The complement system and its role in the pathogenesis of periodontitis: current concepts

    Damgaard, Christian, Holmstrup, Palle, Van Dyke, T. E. & Nielsen, Claus Henrik, Jun 2015, In: Journal of Periodontal Research. 50, 3, p. 283-293 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis

    Hedegaard, C. J., Krakauer, M., Bendtzen, K., Sørensen, Per Soelberg, Sellebjerg, Finn Thorup & Nielsen, Claus Henrik, 1 Oct 2008, In: Clinical Immunology. 129, 1, p. 80-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The flame retardant DE-71 (a mixture of polybrominated diphenyl ethers) inhibits human differentiated thyroid cell function in vitro

    Kronborg, T. M., Hansen, J. F., Rasmussen, Å. K., Vorkamp, K., Nielsen, Claus Henrik, Frederiksen, M., Hofman-Bang, J., Hahn, Christoffer Holst, Ramhøj, L. & Feldt-Rasmussen, Ulla, Jun 2017, In: PloS one. 12, 6, 18 p., e0179858.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The rationale for B lymphocyte depletion in Graves' disease. Monoclonal anti-CD20 antibody therapy as a novel treatment option

    Fassi, Daniel El , Nielsen, Claus Henrik, Hasselbalch, H. K. & Hegedüs, L., 1 May 2006, In: European Journal of Endocrinology. 154, 5, p. 623-32 10 p.

    Research output: Contribution to journal › Journal article › Research

  43. Published

    The redistribution of granulocytes following E. coli endotoxin induced sepsis

    Toft, P., Lillevang, S. T., Tønnesen, E. K., Nielsen, Claus Henrik & Rasmussen, J. W., 1 Nov 1994, In: Acta Anaesthesiologica Scandinavica. 38, 8, p. 852-7 6 p.

    Research output: Contribution to journal › Journal article › Research

  44. Published

    The role of complement in the acquired immune response

    Nielsen, Claus Henrik, Fischer, E. M. & Leslie, R. G., 1 May 2000, In: Immunology. 100, 1, p. 4-12 9 p.

    Research output: Contribution to journal › Journal article › Research

  45. Published

    The role of complement receptor type 1 (CR1, CD35) in determining the cellular distribution of opsonized immune complexes between whole blood cells: kinetic analysis of the buffering capacity of erythrocytes

    Nielsen, Claus Henrik, Matthiesen, S. H., Lyng, I. & Leslie, R. G., 1 Jan 1997, In: Immunology. 90, 1, p. 129-37 9 p.

    Research output: Contribution to journal › Journal article › Research

  46. Published

    The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells

    Nielsen, Claus Henrik, Pedersen, M. L., Marquart, Hanne Vibeke Hansen, Prodinger, W. M. & Leslie, R. G. Q., 1 May 2002, In: European Journal of Immunology. 32, 5, p. 1359-67 9 p.

    Research output: Contribution to journal › Journal article › Research

  47. Published

    The roles of complement receptors type 1 (CR1, CD35) and type 3 (CR3, CD11b/CD18) in the regulation of the immune complex-elicited respiratory burst of polymorphonuclear leukocytes in whole blood

    Nielsen, Claus Henrik, Antonsen, S., Matthiesen, S. H. & Leslie, R. G., 1 Nov 1997, In: European Journal of Immunology. 27, 11, p. 2914-9 6 p.

    Research output: Contribution to journal › Journal article › Research

  48. Published

    The self-antigen, thyroglobulin, induces antigen-experienced CD4+ T cells from healthy donors to proliferate and promote production of the regulatory cytokine, interleukin-10, by monocytes

    Nielsen, Claus Henrik, Galdiers, M. P., Hedegaard, C. J. & Leslie, R. G. Q., 1 Feb 2010, In: Immunology. 129, 2, p. 291-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Thymic stromal lymphopoietin levels after allogeneic hematopoietic stem cell transplantation

    Møller, D. L., Kielsen, K., Nielsen, Claus Henrik, Sengeløv, Henrik, Pedersen, Anders Elm, Ryder, L. P. & Muller, Klaus, 2022, In: Immunopharmacology and Immunotoxicology. 44, 6, p. 1004-1012 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Treated periodontitis and recurrent events after first-time myocardial infarction: A Danish nationwide cohort study

    Wagner, A. K., D'Souza, M., Bang, C. N., Holmstrup, Palle, Blanche, Paul Frédéric, Fiehn, Nils-Erik, Gislason, Gunnar Hilmar, Torp-Pedersen, Christian, Damgaard, Christian, Nielsen, Claus Henrik & Hansen, Peter Riis, 2023, In: Journal of Clinical Periodontology. 50, 10, p. 1305-1314 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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