Treated periodontitis and recurrent events after first-time myocardial infarction: A Danish nationwide cohort study

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Aim: To investigate the association between previous periodontal treatment and recurrent events after first-time myocardial infarction (MI). Materials and Methods: From the Danish nationwide registries, patients with first-time MI between 2000 and 2015 were divided into three groups according to oral health care within 1 year prior to first-time MI. A multiple logistic regression model provided adjusted odds ratios (ORs) with 95% confidence intervals (CIs) to assess the 3-year risk of major adverse cardiovascular events (MACE). Results: A total of 103,949 patients were included. Patients with treated periodontitis (PD) prior to first-time MI had an adjusted 3-year risk of MACE similar to patients presumed periodontally healthy (OR 0.97 [95% CI 0.92–1.03]). Patients with no prior dental visits were significantly older, had more comorbidities and showed significantly increased adjusted 3-year risks of MACE (OR 1.47 [95% CI 1.42–1.52]), cardiovascular death (OR 1.71 [95% CI 1.64–1.78]) and heart failure (OR 1.13 [95% CI 1.07–1.20]) compared with patients presumed periodontally healthy. Conclusions: Patients with treated PD 1 year prior to first-time MI had a similar risk of recurrent cardiovascular events as patients presumed periodontally healthy. No dental visit prior to first-time MI was an independent risk factor for recurrent events.

Original languageEnglish
JournalJournal of Clinical Periodontology
Volume50
Issue number10
Pages (from-to)1305-1314
Number of pages10
ISSN0303-6979
DOIs
Publication statusPublished - 2023

Bibliographical note

Publisher Copyright:
© 2023 The Authors. Journal of Clinical Periodontology published by John Wiley & Sons Ltd.

    Research areas

  • myocardial infarction, periodontal treatment, periodontitis, prognosis, recurrent cardiovascular events

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