TY - JOUR

T1 - Treated periodontitis and recurrent events after first-time myocardial infarction

T2 - A Danish nationwide cohort study

AU - Wagner, Andrea Kjellström

AU - D'Souza, Maria

AU - Bang, Casper N.

AU - Holmstrup, Palle

AU - Blanche, Paul

AU - Fiehn, Nils Erik

AU - Gislason, Gunnar

AU - Pedersen, Christian Torp

AU - Damgaard, Christian

AU - Nielsen, Claus Henrik

AU - Hansen, Peter Riis

N1 - Publisher Copyright: © 2023 The Authors. Journal of Clinical Periodontology published by John Wiley & Sons Ltd.

PY - 2023

Y1 - 2023

N2 - Aim: To investigate the association between previous periodontal treatment and recurrent events after first-time myocardial infarction (MI). Materials and Methods: From the Danish nationwide registries, patients with first-time MI between 2000 and 2015 were divided into three groups according to oral health care within 1 year prior to first-time MI. A multiple logistic regression model provided adjusted odds ratios (ORs) with 95% confidence intervals (CIs) to assess the 3-year risk of major adverse cardiovascular events (MACE). Results: A total of 103,949 patients were included. Patients with treated periodontitis (PD) prior to first-time MI had an adjusted 3-year risk of MACE similar to patients presumed periodontally healthy (OR 0.97 [95% CI 0.92–1.03]). Patients with no prior dental visits were significantly older, had more comorbidities and showed significantly increased adjusted 3-year risks of MACE (OR 1.47 [95% CI 1.42–1.52]), cardiovascular death (OR 1.71 [95% CI 1.64–1.78]) and heart failure (OR 1.13 [95% CI 1.07–1.20]) compared with patients presumed periodontally healthy. Conclusions: Patients with treated PD 1 year prior to first-time MI had a similar risk of recurrent cardiovascular events as patients presumed periodontally healthy. No dental visit prior to first-time MI was an independent risk factor for recurrent events.

AB - Aim: To investigate the association between previous periodontal treatment and recurrent events after first-time myocardial infarction (MI). Materials and Methods: From the Danish nationwide registries, patients with first-time MI between 2000 and 2015 were divided into three groups according to oral health care within 1 year prior to first-time MI. A multiple logistic regression model provided adjusted odds ratios (ORs) with 95% confidence intervals (CIs) to assess the 3-year risk of major adverse cardiovascular events (MACE). Results: A total of 103,949 patients were included. Patients with treated periodontitis (PD) prior to first-time MI had an adjusted 3-year risk of MACE similar to patients presumed periodontally healthy (OR 0.97 [95% CI 0.92–1.03]). Patients with no prior dental visits were significantly older, had more comorbidities and showed significantly increased adjusted 3-year risks of MACE (OR 1.47 [95% CI 1.42–1.52]), cardiovascular death (OR 1.71 [95% CI 1.64–1.78]) and heart failure (OR 1.13 [95% CI 1.07–1.20]) compared with patients presumed periodontally healthy. Conclusions: Patients with treated PD 1 year prior to first-time MI had a similar risk of recurrent cardiovascular events as patients presumed periodontally healthy. No dental visit prior to first-time MI was an independent risk factor for recurrent events.

KW - myocardial infarction

KW - periodontal treatment

KW - periodontitis

KW - prognosis

KW - recurrent cardiovascular events

U2 - 10.1111/jcpe.13853

DO - 10.1111/jcpe.13853

M3 - Journal article

C2 - 37464548

AN - SCOPUS:85165381148

VL - 50

SP - 1305

EP - 1314

JO - Journal of Clinical Periodontology

JF - Journal of Clinical Periodontology

SN - 0303-6979

IS - 10

ER -