Claus Henrik Nielsen

Claus Henrik Nielsen

Professor


  1. 1993
  2. Published

    Changes in blood levels of proteinase inhibitors, pregnancy zone protein, steroid carriers and complement factors induced by oral contraceptives

    Nielsen, Claus Henrik, Poulsen, H. K., Teisner, B., Thorsen, P., Hau, J. & Westergaard, J. G., 1 Sep 1993, In: European Journal of Obstetrics & Gynecology and Reproductive Biology. 51, 1, p. 63-71 9 p.

    Research output: Contribution to journalJournal articleResearch

  3. 1994
  4. Published

    Interactions of opsonized immune complexes with whole blood cells: binding to erythrocytes restricts complex uptake by leucocyte populations

    Nielsen, Claus Henrik, Svehag, S. E., Marquart, Hanne Vibeke Hansen & Leslie, R. G., 1 Aug 1994, In: Scandinavian Journal of Immunology. 40, 2, p. 228-36 9 p.

    Research output: Contribution to journalJournal articleResearch

  5. Published

    The redistribution of granulocytes following E. coli endotoxin induced sepsis

    Toft, P., Lillevang, S. T., Tønnesen, E. K., Nielsen, Claus Henrik & Rasmussen, J. W., 1 Nov 1994, In: Acta Anaesthesiologica Scandinavica. 38, 8, p. 852-7 6 p.

    Research output: Contribution to journalJournal articleResearch

  6. 1995
  7. Published

    Complement receptor expression and activation of the complement cascade on B lymphocytes from patients with systemic lupus erythematosus (SLE)

    Marquart, Hanne Vibeke Hansen, Svendsen, A., Rasmussen, J. M., Nielsen, Claus Henrik, Junker, P., Svehag, S. E. & Leslie, R. G., 1 Jul 1995, In: Clinical and Experimental Immunology. 101, 1, p. 60-5 6 p.

    Research output: Contribution to journalJournal articleResearch

  8. 1997
  9. Published

    Effect of methylprednisolone on the oxidative burst activity, adhesion molecules and clinical outcome following open heart surgery

    Toft, P., Christiansen, K., Tønnesen, E. K., Nielsen, Claus Henrik & Lillevang, S., 1 Jan 1997, In: Scandinavian Cardiovascular Journal. 31, 5, p. 283-8 6 p.

    Research output: Contribution to journalJournal articleResearch

  10. Published

    Expression of adhesion and activation molecules on lymphocytes during open-heart surgery with cardiopulmonary bypass

    Toft, P., Tønnesen, E. K., Zülow, I., Nielsen, Claus Henrik & Hokland, M., 1 Jan 1997, In: Scandinavian Cardiovascular Journal. 31, 2, p. 91-5 5 p.

    Research output: Contribution to journalJournal articleResearch

  11. Published

    The role of complement receptor type 1 (CR1, CD35) in determining the cellular distribution of opsonized immune complexes between whole blood cells: kinetic analysis of the buffering capacity of erythrocytes

    Nielsen, Claus Henrik, Matthiesen, S. H., Lyng, I. & Leslie, R. G., 1 Jan 1997, In: Immunology. 90, 1, p. 129-37 9 p.

    Research output: Contribution to journalJournal articleResearch

  12. Published

    The roles of complement receptors type 1 (CR1, CD35) and type 3 (CR3, CD11b/CD18) in the regulation of the immune complex-elicited respiratory burst of polymorphonuclear leukocytes in whole blood

    Nielsen, Claus Henrik, Antonsen, S., Matthiesen, S. H. & Leslie, R. G., 1 Nov 1997, In: European Journal of Immunology. 27, 11, p. 2914-9 6 p.

    Research output: Contribution to journalJournal articleResearch

  13. 1998
  14. Published

    Diminished ability of erythrocytes from patients with systemic lupus erythematosus to limit opsonized immune complex deposition on leukocytes and activation of granulocytes

    Nielsen, Claus Henrik, Rasmussen, J. M., Voss, A., Junker, P. & Leslie, R. G., 1 Apr 1998, In: Arthritis & Rheumatism. 41, 4, p. 613-22 10 p.

    Research output: Contribution to journalJournal articleResearch

  15. Published

    Changes in adhesion molecule expression and oxidative burst activity of granulocytes and monocytes during open-heart surgery with cardiopulmonary bypass compared with abdominal surgery

    Toft, P., Nielsen, Claus Henrik, Tønnesen, E. K., Hansen, T. G. & Hokland, M., 1 May 1998, In: European Journal of Anaesthesiology. 15, 3, p. 345-53 9 p.

    Research output: Contribution to journalJournal articleResearch

  16. 2000
  17. Published

    The role of complement in the acquired immune response

    Nielsen, Claus Henrik, Fischer, E. M. & Leslie, R. G., 1 May 2000, In: Immunology. 100, 1, p. 4-12 9 p.

    Research output: Contribution to journalJournal articleResearch

  18. 2001
  19. Published

    Natural autoantibodies and complement promote the uptake of a self antigen, human thyroglobulin, by B cells and the proliferation of thyroglobulin-reactive CD4(+) T cells in healthy individuals

    Nielsen, Claus Henrik, Leslie, R. G., Jepsen, B. S., Kazatchkine, M. D., Kaveri, S. V. & Fischer, E., 1 Sep 2001, In: European Journal of Immunology. 31, 9, p. 2660-8 9 p.

    Research output: Contribution to journalJournal articleResearch

  20. Published

    CR2-mediated activation of the complement alternative pathway results in formation of membrane attack complexes on human B lymphocytes

    Nielsen, Claus Henrik, Marquart, Hanne Vibeke Hansen, Prodinger, W. M. & Leslie, R. G., 1 Dec 2001, In: Immunology. 104, 4, p. 418-22 5 p.

    Research output: Contribution to journalJournal articleResearch

  21. 2002
  22. Published

    The role of complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) in promoting C3 fragment deposition and membrane attack complex formation on normal peripheral human B cells

    Nielsen, Claus Henrik, Pedersen, M. L., Marquart, Hanne Vibeke Hansen, Prodinger, W. M. & Leslie, R. G. Q., 1 May 2002, In: European Journal of Immunology. 32, 5, p. 1359-67 9 p.

    Research output: Contribution to journalJournal articleResearch

  23. Published

    Complement's participation in acquired immunity

    Nielsen, Claus Henrik & Leslie, R. G. Q., 1 Aug 2002, In: Journal of Leukocyte Biology. 72, 2, p. 249-61 13 p.

    Research output: Contribution to journalJournal articleResearch

  24. 2003
  25. Published

    Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes

    Leslie, R. G. Q., Prodinger, W. M. & Nielsen, Claus Henrik, 1 Dec 2003, In: European Journal of Immunology. 33, 12, p. 3311-21 11 p.

    Research output: Contribution to journalJournal articleResearch

  26. 2004
  27. Published

    Autoantibodies in autoimmune thyroid disease promote immune complex formation with self antigens and increase B cell and CD4+ T cell proliferation in response to self antigens

    Nielsen, Claus Henrik, Hegedüs, L. & Leslie, R. G. Q., 1 Jan 2004, In: European Journal of Immunology. 34, 1, p. 263-72 10 p.

    Research output: Contribution to journalJournal articleResearch

  28. Published

    The classical and alternative pathways of complement activation play distinct roles in spontaneous C3 fragment deposition and membrane attack complex (MAC) formation on human B lymphocytes

    Leslie, R. G. Q. & Nielsen, Claus Henrik, 1 Jan 2004, In: Immunology. 111, 1, p. 86-90 5 p.

    Research output: Contribution to journalJournal articleResearch

  29. 2006
  30. Published

    GABA(A) receptor function is regulated by lipid bilayer elasticity

    Søgaard, R., Werge, T. M., Bertelsen, C., Lundbye, C., Madsen, Kenneth Lindegaard, Nielsen, Claus Henrik & Lundbaek, J. A., 2006, In: Biochemistry. 45, 43, p. 13118-29 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Immunological characteristics of subjects with asymptomatic skin sensitization to birch and grass pollen

    Assing, K., Nielsen, Claus Henrik & Poulsen, Lars K., 1 Mar 2006, In: Clinical and Experimental Allergy. 36, 3, p. 283-92 10 p.

    Research output: Contribution to journalJournal articleResearch

  32. Published

    Self-reactive CD4+ T cells and B cells in the blood in health and autoimmune disease: increased frequency of thyroglobulin-reactive cells in Graves' disease

    Nielsen, Claus Henrik, Moeller, A. C., Hegedüs, L., Bendtzen, K. & Leslie, R. G. Q., 1 Mar 2006, In: Journal of Clinical Immunology. 26, 2, p. 126-37 12 p.

    Research output: Contribution to journalJournal articleResearch

  33. Published

    Differential effect of conditioning regimens on cytokine responses during allogeneic stem cell transplantation

    Andersen, J., Heilmann, C., Jacobsen, N., Nielsen, Claus Henrik, Bendtzen, K. & Müller, K., 1 Apr 2006, In: Bone Marrow Transplantation. 37, 7, p. 635-40 6 p.

    Research output: Contribution to journalJournal articleResearch

  34. Published

    The rationale for B lymphocyte depletion in Graves' disease. Monoclonal anti-CD20 antibody therapy as a novel treatment option

    Fassi, Daniel El , Nielsen, Claus Henrik, Hasselbalch, H. K. & Hegedüs, L., 1 May 2006, In: European Journal of Endocrinology. 154, 5, p. 623-32 10 p.

    Research output: Contribution to journalJournal articleResearch

  35. Published

    Class switch recombination in selective IgA-deficient subjects

    Jensen, L. H., Ryder, L. P., Nielsen, L. K., Nielsen, Claus Henrik & Poulsen, Lars K., 1 Jun 2006, In: Clinical and Experimental Immunology. 144, 3, p. 458-66 9 p.

    Research output: Contribution to journalJournal articleResearch

  36. Published

    Surfactant protein D is proatherogenic in mice

    Sorensen, G. L., Madsen, J., Kejling, K., Tornoe, I., Nielsen, O., Townsend, P., Poulain, F., Nielsen, Claus Henrik, Reid, K. B. M., Hawgood, S., Falk, E. & Holmskov, U., 1 Jun 2006, In: American Journal of Physiology: Heart and Circulatory Physiology. 290, 6, p. H2286-94

    Research output: Contribution to journalJournal articleResearch

  37. Published

    Treatment-resistant severe, active Graves' ophthalmopathy successfully treated with B lymphocyte depletion

    Fassi, Daniel El , Nielsen, Claus Henrik, Hasselbalch, H. K. & Hegedüs, L., 1 Jul 2006, In: Thyroid. 16, 7, p. 709-10 2 p.

    Research output: Contribution to journalJournal articleResearch

  38. Published

    Increased plasma levels of IL-6 in bacteremic periodontis patients after scaling

    Forner, L., Nielsen, Claus Henrik, Bendtzen, K., Larsen, Tove & Holmstrup, Palle, 1 Oct 2006, In: Journal of Clinical Periodontology. 33, 10, p. 724-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Rituximab (MabThera) til behandling af aktiv reumatoid artritis

    Fassi, Daniel El , Nielsen, Claus Henrik & Bendtzen, K., 20 Nov 2006, In: Ugeskrift for Laeger. 168, 47, p. 4079-81 3 p.

    Research output: Contribution to journalJournal articleResearch

  40. 2007
  41. Published

    Production of interleukin (IL)-5 and IL-10 accompanies T helper cell type 1 (Th1) cytokine responses to a major thyroid self-antigen, thyroglobulin, in health and autoimmune thyroid disease

    Nielsen, Claus Henrik, Hegedüs, L., Rieneck, K., Moeller, A. C., Leslie, R. G. Q. & Bendtzen, K., 1 Feb 2007, In: Clinical and Experimental Immunology. 147, 2, p. 287-95 9 p.

    Research output: Contribution to journalJournal articleResearch

  42. Published

    B lymphocyte depletion with the monoclonal antibody rituximab in Graves' disease: a controlled pilot study

    Fassi, Daniel El , Nielsen, Claus Henrik, Bonnema, S. J., Hasselbalch, H. K. & Hegedüs, L., 1 May 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 5, p. 1769-72 4 p.

    Research output: Contribution to journalJournal articleResearch

  43. Published

    Gene expression profiling in autoimmune diseases: chronic inflammation or disease specific patterns?

    Bovin, L. F., Brynskov, J., Hegedüs, L., Jess, T., Nielsen, Claus Henrik & Bendtzen, K., 1 May 2007, In: Autoimmunity. 40, 3, p. 191-201 11 p.

    Research output: Contribution to journalJournal articleResearch

  44. Published

    Methotrexate induces poly(ADP-ribose) polymerase-dependent, caspase 3-independent apoptosis in subsets of proliferating CD4+ T cells

    Nielsen, Claus Henrik, Albertsen, L., Bendtzen, K. & Baslund, B., 1 May 2007, In: Clinical and Experimental Immunology. 148, 2, p. 288-95 8 p.

    Research output: Contribution to journalJournal articleResearch

  45. Published

    B-cell depletion with rituximab in the treatment of autoimmune diseases. Graves' ophthalmopathy the latest addition to an expanding family

    Nielsen, Claus Henrik, Fassi, Daniel El , Hasselbalch, H. K., Bendtzen, K. & Hegedüs, L., 1 Jul 2007, In: Expert Opinion on Biological Therapy. 7, 7, p. 1061-78 18 p.

    Research output: Contribution to journalJournal articleResearch

  46. Published

    Evidence of intrathyroidal B-lymphocyte depletion after rituximab therapy in a patient with Graves' disease

    Fassi, Daniel El , Clemmensen, O., Nielsen, Claus Henrik, Silkiss, R. Z. & Hegedüs, L., 1 Oct 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 10, p. 3762-3 2 p.

    Research output: Contribution to journalJournal articleResearch

  47. 2008
  48. Published
  49. Published
  50. Published
  51. Published

    Treatment of Graves' disease with rituximab specifically reduces the production of thyroid stimulating autoantibodies

    Fassi, Daniel El , Banga, J. P., Gilbert, J. A., Padoa, C., Hegedüs, L. & Nielsen, Claus Henrik, 2008, In: Clinical Immunology. 130, 3, p. 252-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published
  53. Published

    Reduced folate carrier polymorphism determines methotrexate uptake by B cells and CD4+ T cells

    Baslund, B., Gregers, J. & Nielsen, Claus Henrik, 1 Apr 2008, In: Rheumatology. 47, 4, p. 451-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Ulcerative colitis following B lymphocyte depletion with rituximab in a patient with Graves' disease

    Fassi, Daniel El , Nielsen, Claus Henrik, Kjeldsen, J. B., Clemmensen, O. & Hegedüs, L., 1 May 2008, In: Gut. 57, 5, p. 714-5 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Enhancement of human adaptive immune responses by administration of a high-molecular-weight polysaccharide extract from the cyanobacterium Arthrospira platensis

    Løbner, M., Walsted, A., Larsen, R., Bendtzen, K. & Nielsen, Claus Henrik, 1 Jun 2008, In: Journal of Medicinal Food. 11, 2, p. 313-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Biologiske behandlingsmuligheder ved Graves' oftalmopati

    Fassi, Daniel El , Nielsen, Claus Henrik & Hegedüs, L., 9 Jun 2008, In: Ugeskrift for Laeger. 170, 24, p. 2128-30 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Nye behandlinger af Graves' sygdom med fokus på det B-lymfocyt-depleterende antistof rituximab

    Nielsen, Claus Henrik, Fassi, Daniel El & Hegedüs, L., 9 Jun 2008, In: Ugeskrift for Laeger. 170, 24, p. 2131-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Application of new therapies in Graves' disease and thyroid-associated ophthalmopathy: animal models and translation to human clinical trials

    Banga, J. P., Nielsen, Claus Henrik, Gilbert, J. A., Fassi, Daniel El & Hegedus, L., 1 Sep 2008, In: Thyroid. 18, 9, p. 973-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Epitope recognition patterns of thyroid peroxidase autoantibodies in healthy individuals and patients with Hashimoto's thyroiditis*

    Nielsen, Claus Henrik, Brix, T. H., Gardas, A., Banga, J. P. & Hegedüs, L., 1 Oct 2008, In: Clinical Endocrinology. 69, 4, p. 664-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis

    Hedegaard, C. J., Krakauer, M., Bendtzen, K., Lund, H., Sellebjerg, Finn Thorup & Nielsen, Claus Henrik, 1 Oct 2008, In: Immunology. 125, 2, p. 161-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis

    Hedegaard, C. J., Krakauer, M., Bendtzen, K., Sørensen, Per Soelberg, Sellebjerg, Finn Thorup & Nielsen, Claus Henrik, 1 Oct 2008, In: Clinical Immunology. 129, 1, p. 80-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. 2009
  63. Published

    A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase

    Nielsen, Claus Henrik, Brix, T. H., Leslie, R. G. Q. & Hegedüs, L., 2009, In: Clinical Immunology. 133, 2, p. 218-27 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Decreased interleukin-2 responses to Fusobacterium nucleatum and Porphyromonas gingivalis in generalized aggressive periodontitis

    Borch, T. S., Løbner, M., Bendtzen, K., Holmstrup, Palle & Nielsen, Claus Henrik, 2009, In: Journal of Periodontology. 80, 5, p. 800-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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