Epitope recognition patterns of thyroid peroxidase autoantibodies in healthy individuals and patients with Hashimoto's thyroiditis*
Research output: Contribution to journal › Journal article › Research › peer-review
Thyroid peroxidase antibodies (TPOAb) are markers of autoimmune thyroid disease (AITD), including Hashimoto's thyroiditis (HT), but naturally occurring TPOAb are also detectable in healthy, euthyroid individuals. In AITD, circulating TPOAb react mainly with two immunodominant regions (IDR), IDR-A and IDR-B. The present study was undertaken in order to compare the epitope recognition pattern of TPOAb in HT patients and healthy subjects.
Original language | English |
---|---|
Journal | Clinical Endocrinology |
Volume | 69 |
Issue number | 4 |
Pages (from-to) | 664-8 |
Number of pages | 5 |
ISSN | 0300-0664 |
DOIs | |
Publication status | Published - 1 Oct 2008 |
ID: 34157587