Current controversies, is there merit?

Research output: Contribution to journal › Journal article › Research › peer-review

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Current controversies, is there merit? / Twetman, S.

In: Advances in Dental Research, Vol. 21, No. 1, 2009, p. 48-52.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Twetman, S 2009, 'Current controversies, is there merit?', Advances in Dental Research, vol. 21, no. 1, pp. 48-52. https://doi.org/10.1177/0895937409335624

APA

Twetman, S. (2009). Current controversies, is there merit? Advances in Dental Research, 21(1), 48-52. https://doi.org/10.1177/0895937409335624

Vancouver

Twetman S. Current controversies, is there merit? Advances in Dental Research. 2009;21(1):48-52. https://doi.org/10.1177/0895937409335624

Author

Twetman, S. / Current controversies, is there merit?. In: Advances in Dental Research. 2009 ; Vol. 21, No. 1. pp. 48-52.

Bibtex

@article{c3773840ab8311df928f000ea68e967b,
title = "Current controversies, is there merit?",
abstract = "Xylitol has become a debated measure in caries prevention. This paper aims to examine and comment on some possible controversies, with emphasis on the most recent literature. A search for clinical trials was conducted through 2007 in PubMed, and papers describing a controlled xylitol intervention with reported endpoints were assessed. The main reasons for the conflicting results were weak study designs, underpowered groups, mixed outcome measures, and use of low-xylitol regimens. Definitive evidence for a caries-preventive effectiveness of xylitol is still lacking, and it is concluded that the controversies cannot be solved without well-designed double-blind randomized placebo-controlled caries trials in defined populations. Furthermore, as a candidate for public health intervention, the economical aspects of xylitol administration must be taken into account at the planning stages of future projects. Until further evidence is available, xylitol should be regarded as an adjunct to other preventive measures in targeted individuals.",
author = "S Twetman",
year = "2009",
doi = "10.1177/0895937409335624",
language = "English",
volume = "21",
pages = "48--52",
journal = "Advances in dental research",
issn = "0895-9374",
publisher = "International and American Associations for Dental Research",
number = "1",

}

RIS

TY - JOUR

T1 - Current controversies, is there merit?

AU - Twetman, S

PY - 2009

Y1 - 2009

N2 - Xylitol has become a debated measure in caries prevention. This paper aims to examine and comment on some possible controversies, with emphasis on the most recent literature. A search for clinical trials was conducted through 2007 in PubMed, and papers describing a controlled xylitol intervention with reported endpoints were assessed. The main reasons for the conflicting results were weak study designs, underpowered groups, mixed outcome measures, and use of low-xylitol regimens. Definitive evidence for a caries-preventive effectiveness of xylitol is still lacking, and it is concluded that the controversies cannot be solved without well-designed double-blind randomized placebo-controlled caries trials in defined populations. Furthermore, as a candidate for public health intervention, the economical aspects of xylitol administration must be taken into account at the planning stages of future projects. Until further evidence is available, xylitol should be regarded as an adjunct to other preventive measures in targeted individuals.

AB - Xylitol has become a debated measure in caries prevention. This paper aims to examine and comment on some possible controversies, with emphasis on the most recent literature. A search for clinical trials was conducted through 2007 in PubMed, and papers describing a controlled xylitol intervention with reported endpoints were assessed. The main reasons for the conflicting results were weak study designs, underpowered groups, mixed outcome measures, and use of low-xylitol regimens. Definitive evidence for a caries-preventive effectiveness of xylitol is still lacking, and it is concluded that the controversies cannot be solved without well-designed double-blind randomized placebo-controlled caries trials in defined populations. Furthermore, as a candidate for public health intervention, the economical aspects of xylitol administration must be taken into account at the planning stages of future projects. Until further evidence is available, xylitol should be regarded as an adjunct to other preventive measures in targeted individuals.

U2 - 10.1177/0895937409335624

DO - 10.1177/0895937409335624

M3 - Journal article

C2 - 19717410

VL - 21

SP - 48

EP - 52

JO - Advances in dental research

JF - Advances in dental research

SN - 0895-9374

IS - 1

ER -

ID: 21483862