Effectiveness of high-fluoride toothpaste on enamel demineralization during orthodontic treatment: a multicenter randomized controlled trial
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Effectiveness of high-fluoride toothpaste on enamel demineralization during orthodontic treatment : a multicenter randomized controlled trial. / Sonesson, Mikael; Twetman, Svante; Bondemark, Lars.
In: European Journal of Orthodontics, Vol. 36, No. 6, 2014, p. 678-682.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Effectiveness of high-fluoride toothpaste on enamel demineralization during orthodontic treatment
T2 - a multicenter randomized controlled trial
AU - Sonesson, Mikael
AU - Twetman, Svante
AU - Bondemark, Lars
PY - 2014
Y1 - 2014
N2 - SUMMARY OBJECTIVE: To evaluate the effectiveness of daily tooth brushing with high-fluoride toothpaste on white spot lesion (WSL) formation in adolescents during treatment with fixed orthodontic appliances (FOA). MATERIALS AND METHODS: Four hundred and twenty-four healthy 11- to 16-year-old patients, referred to five Orthodontic Specialist Clinics, were randomized to use either toothpaste containing 5000 ppm fluoride or regular toothpaste with 1450 ppm fluoride. To be eligible for inclusion, the patients had to be scheduled for bimaxillary treatment with FOA for an expected duration of at least 1 year. The primary and secondary outcome measures were prevalence and incidence of WSL, as registered from digital photos of the maxillary incisors, canines, and premolars taken before onset and immediately after debonding. The photos were evaluated separately by two blinded and calibrated clinicians using a 4-step score. A random sample of 50 cases was reassessed to check intra- and interexaminer reliability (Kappa = 0.70; 0.74). RESULTS: The use of high-fluoride toothpaste resulted in fewer WSL (P = 0.042) with a prevented fraction of 32%. The lateral incisor was most commonly affected in both groups. CONCLUSION: To prevent WSL during treatment of FOA, daily use of high-fluoride toothpaste may be recommended.
AB - SUMMARY OBJECTIVE: To evaluate the effectiveness of daily tooth brushing with high-fluoride toothpaste on white spot lesion (WSL) formation in adolescents during treatment with fixed orthodontic appliances (FOA). MATERIALS AND METHODS: Four hundred and twenty-four healthy 11- to 16-year-old patients, referred to five Orthodontic Specialist Clinics, were randomized to use either toothpaste containing 5000 ppm fluoride or regular toothpaste with 1450 ppm fluoride. To be eligible for inclusion, the patients had to be scheduled for bimaxillary treatment with FOA for an expected duration of at least 1 year. The primary and secondary outcome measures were prevalence and incidence of WSL, as registered from digital photos of the maxillary incisors, canines, and premolars taken before onset and immediately after debonding. The photos were evaluated separately by two blinded and calibrated clinicians using a 4-step score. A random sample of 50 cases was reassessed to check intra- and interexaminer reliability (Kappa = 0.70; 0.74). RESULTS: The use of high-fluoride toothpaste resulted in fewer WSL (P = 0.042) with a prevented fraction of 32%. The lateral incisor was most commonly affected in both groups. CONCLUSION: To prevent WSL during treatment of FOA, daily use of high-fluoride toothpaste may be recommended.
U2 - 10.1093/ejo/cjt096
DO - 10.1093/ejo/cjt096
M3 - Journal article
C2 - 24375756
AN - SCOPUS:84922507643
VL - 36
SP - 678
EP - 682
JO - European Journal of Orthodontics
JF - European Journal of Orthodontics
SN - 0141-5387
IS - 6
ER -
ID: 213041648