Enhancement of natural killer cell activity in healthy subjects by Immulina®, a Spirulina extract enriched for Braun-type lipoproteins

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Immulina®, a commercial extract of Arthrospira (Spirulina) platensis is a potent activator of THP-1 monocytes and CD4+ T cells IN VITRO and enhances several immunological functions in mice. We further characterized Immulina® by determining that Braun-type lipoproteins are responsible for a major portion of the IN VITRO monocyte activation exhibited by this material. In order to understand the effect of Immulina® on NK cell activity, a pilot study was conducted on ten healthy North American individuals who supplemented their diet with Immulina® (400¿mg/day) for seven days. We observed a 40¿% average increase in the killing of K562 tumor cells by NK cells (p¿
Original languageEnglish
JournalPlanta Medica
Volume76
Issue number16
Pages (from-to)1802-8
Number of pages7
ISSN0032-0943
DOIs
Publication statusPublished - 1 Nov 2010

ID: 34071792