Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives
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Periodontal microbiology and microbial etiology of periodontal diseases : Historical concepts and contemporary perspectives. / Belibasakis, Georgios N.; Belstrøm, Daniel; Eick, Sigrun; Gursoy, Ulvi K.; Johansson, Anders; Könönen, Eija.
In: Periodontology 2000, 2024.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - Periodontal microbiology and microbial etiology of periodontal diseases
T2 - Historical concepts and contemporary perspectives
AU - Belibasakis, Georgios N.
AU - Belstrøm, Daniel
AU - Eick, Sigrun
AU - Gursoy, Ulvi K.
AU - Johansson, Anders
AU - Könönen, Eija
N1 - Publisher Copyright: © 2023 The Authors. Periodontology 2000 published by John Wiley & Sons Ltd.
PY - 2024
Y1 - 2024
N2 - This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis-centered interpretation. Reference is made to anerobic microbiology and to the discovery of select periodontal pathogens and their virulence factors, as well as to biofilms. The evolution of contemporary molecular methods and high-throughput platforms is highlighted in appreciating the breadth and depth of the periodontal microbiome. Finally clinical microbiology is brought into perspective with the contribution of different microbial species in periodontal diagnosis, the combination of microbial and host biomarkers for this purpose, and the use of antimicrobials in the treatment of the disease.
AB - This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis-centered interpretation. Reference is made to anerobic microbiology and to the discovery of select periodontal pathogens and their virulence factors, as well as to biofilms. The evolution of contemporary molecular methods and high-throughput platforms is highlighted in appreciating the breadth and depth of the periodontal microbiome. Finally clinical microbiology is brought into perspective with the contribution of different microbial species in periodontal diagnosis, the combination of microbial and host biomarkers for this purpose, and the use of antimicrobials in the treatment of the disease.
KW - anaerobic
KW - antibiotics
KW - antimicrobial
KW - biofilms
KW - clinical microbial diagnostics
KW - etiology
KW - European
KW - host biomarkers
KW - pathogens
KW - periodontal microbiology
U2 - 10.1111/prd.12473
DO - 10.1111/prd.12473
M3 - Review
C2 - 36661184
AN - SCOPUS:85147022674
JO - Periodontology 2000
JF - Periodontology 2000
SN - 0906-6713
ER -
ID: 335353676