Claus Henrik Nielsen

Claus Henrik Nielsen

Professor

ORCID: 0000-0001-7543-9016

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  1. Published

    Diminished ability of erythrocytes from patients with systemic lupus erythematosus to limit opsonized immune complex deposition on leukocytes and activation of granulocytes

    Nielsen, Claus Henrik, Rasmussen, J. M., Voss, A., Junker, P. & Leslie, R. G., 1 Apr 1998, In: Arthritis & Rheumatism. 41, 4, p. 613-22 10 p.

    Research output: Contribution to journal › Journal article › Research

  2. Published

    Does a causal relation between cardiovascular disease and periodontitis exist?

    Midjord-Belstrøm, Daniel, Damgaard, Christian, Nielsen, Claus Henrik & Holmstrup, Palle, May 2012, In: Microbes and Infection. 14, 5, p. 411-8 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Effect of methylprednisolone on the oxidative burst activity, adhesion molecules and clinical outcome following open heart surgery

    Toft, P., Christiansen, K., Tønnesen, E. K., Nielsen, Claus Henrik & Lillevang, S., 1 Jan 1997, In: Scandinavian Cardiovascular Journal. 31, 5, p. 283-8 6 p.

    Research output: Contribution to journal › Journal article › Research

  4. Published

    Effects of the Commercial Flame Retardant Mixture DE-71 on Cytokine Production by Human Immune Cells

    Mynster Kronborg, T., Hansen, J. F., Nielsen, Claus Henrik, Ramhøj, L., Frederiksen, M., Vorkamp, K. & Feldt-Rasmussen, Ulla, 2016, In: PLOS ONE. 11, 4, 13 p., e0154621.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Enhancement of human adaptive immune responses by administration of a high-molecular-weight polysaccharide extract from the cyanobacterium Arthrospira platensis

    Løbner, M., Walsted, A., Larsen, R., Bendtzen, K. & Nielsen, Claus Henrik, 1 Jun 2008, In: Journal of Medicinal Food. 11, 2, p. 313-22 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Enhancement of natural killer cell activity in healthy subjects by Immulina®, a Spirulina extract enriched for Braun-type lipoproteins

    Nielsen, Claus Henrik, Balachandran, P., Christensen, O., Pugh, N. D., Tamta, H., Sufka, K. J., Wu, X., Walsted, A., Schjørring-Thyssen, M., Enevold, Christian & Pasco, D. S., 1 Nov 2010, In: Planta Medica. 76, 16, p. 1802-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Epitope recognition patterns of thyroid peroxidase autoantibodies in healthy individuals and patients with Hashimoto's thyroiditis*

    Nielsen, Claus Henrik, Brix, T. H., Gardas, A., Banga, J. P. & Hegedüs, L., 1 Oct 2008, In: Clinical Endocrinology. 69, 4, p. 664-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Erythrocytes restrict microvesicle-induced production of reactive oxygen species by polymorphonuclear leukocytes

    Winberg, L. K., Rasmussen, N. S., Nielsen, Claus Henrik & Jacobsen, Søren, 2019, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 27, 7, p. 538-542 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Evidence of intrathyroidal B-lymphocyte depletion after rituximab therapy in a patient with Graves' disease

    Fassi, Daniel El , Clemmensen, O., Nielsen, Claus Henrik, Silkiss, R. Z. & Hegedüs, L., 1 Oct 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 10, p. 3762-3 2 p.

    Research output: Contribution to journal › Journal article › Research

  10. Published

    Evidence of orbital B and T cell depletion after rituximab therapy in Graves' ophthalmopathy

    Nielsen, J. F., El Fassi, D., Nielsen, Claus Henrik, Hegedüs, L., Lauer, S. A., Silkiss, R. Z., Prause, J. U., Nielsen, J. F., Fassi, Daniel El , Nielsen, C. H., Hegedüs, L., Lauer, S. A., Silkiss, R. Z. & Prause, J. U., 1 Nov 2009, In: Acta Ophthamologica (Online). 87, 8, p. 927-9 3 p.

    Research output: Contribution to journal › Journal article › Research

  11. Published

    Expanding the citrullinome of synovial fibrinogen from rheumatoid arthritis patients

    Sharma, M., Danigaard, D., Senolt, L., Svensson, B., Bay-Jensen, A., Nielsen, Claus Henrik & Hägglund, Per Mårten, 2019, In: Journal of Proteomics. 208, 103484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Expression of adhesion and activation molecules on lymphocytes during open-heart surgery with cardiopulmonary bypass

    Toft, P., Tønnesen, E. K., Zülow, I., Nielsen, Claus Henrik & Hokland, M., 1 Jan 1997, In: Scandinavian Cardiovascular Journal. 31, 2, p. 91-5 5 p.

    Research output: Contribution to journal › Journal article › Research

  13. Published

    GABA(A) receptor function is regulated by lipid bilayer elasticity

    Søgaard, R., Werge, T. M., Bertelsen, C., Lundbye, C., Madsen, Kenneth Lindegaard, Nielsen, Claus Henrik & Lundbaek, J. A., 2006, In: Biochemistry. 45, 43, p. 13118-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Gene expression profiling in autoimmune diseases: chronic inflammation or disease specific patterns?

    Bovin, L. F., Brynskov, J., Hegedüs, L., Jess, T., Nielsen, Claus Henrik & Bendtzen, K., 1 May 2007, In: Autoimmunity. 40, 3, p. 191-201 11 p.

    Research output: Contribution to journal › Journal article › Research

  15. Published

    Generation of monoclonal antibodies against peptidylarginine deiminase 2 (PAD2) and development of a PAD2-specific enzyme-linked immunosorbent assay

    Damgaard, D., Palarasah, Y., Skjødt, K., Catrina, A. I., Hensen, S. M. M., Pruijn, G. J. M. & Nielsen, Claus Henrik, Mar 2014, In: Journal of Immunological Methods. 405, p. 15-22 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Genetic polymorphisms of dsRNA ligating pattern recognition receptors TLR3, MDA5, and RIG-I. Association with systemic lupus erythematosus and clinical phenotypes

    Enevold, Christian, Kjaer, L., Nielsen, Claus Henrik, Voss, A., Jacobsen, R. S., Hermansen, M. F., Redder, L., Oturai, A. B., Jensen, P. E., Bendtzen, K. & Jacobsen, Søren, 2014, In: Rheumatology International. 34, 10, p. 1401-1408 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Glatiramer acetate antibodies, gene expression and disease activity in multiple sclerosis

    Sellebjerg, Finn Thorup, Hedegaard, C. J., Krakauer, M., Hesse, D., Lund, H., Nielsen, Claus Henrik, Søndergaard, H. B. & Sørensen, Per Soelberg, 2011, In: Multiple Sclerosis.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Identification of Novel Native Autoantigens in Rheumatoid Arthritis

    Poulsen, T. B. G., Damgaard, D., Jørgensen, M. M., Senolt, L., Blackburn, J. M., Nielsen, Claus Henrik & Stensballe, A., 2020, In: Biomedicines. 8, 6, 13 p., 141.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Immunoglobulin G antibodies against Porphyromonas gingivalis or Aggregatibacter actinomycetemcomitans in cardiovascular disease and periodontitis

    Damgaard, Christian, Reinholdt, J., Enevold, C., Fiehn, Nils-Erik, Nielsen, Claus Henrik & Holmstrup, Palle, 2017, In: Journal of Oral Microbiology. 9, 1, 1374154.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Immunological characteristics of subjects with asymptomatic skin sensitization to birch and grass pollen

    Assing, K., Nielsen, Claus Henrik & Poulsen, Lars K., 1 Mar 2006, In: Clinical and Experimental Allergy. 36, 3, p. 283-92 10 p.

    Research output: Contribution to journal › Journal article › Research

  21. Published

    In vitro complement activation, adherence to red blood cells and induction of mononuclear cell cytokine production by four strains of Aggregatibacter actinomycetemcomitans with different fimbriation and expression of leukotoxin

    Damgaard, Christian, Reinholdt, J., Palarasah, Y., Enevold, Christian, Nielsen, C., Brimnes, M. K., Holmstrup, Palle & Nielsen, Claus Henrik, 2017, In: Journal of Periodontal Research. 52, 3, p. 485-496 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    In vitro cytokine responses to periodontal pathogens: generalized aggressive periodontitis is associated with increased IL-6 response to Porphyromonas gingivalis

    Borch, T. S., Holmstrup, P., Bendtzen, K. & Nielsen, Claus Henrik, 1 Jun 2010, In: Scandinavian Journal of Immunology. 71, 6, p. 440-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Increased levels of peptidylarginine deiminase 2 in synovial fluid from anti-CCP-positive rheumatoid arthritis patients: Association with disease activity and inflammatory markers

    Damgaard, D., Senolt, L. & Nielsen, Claus Henrik, 15 Feb 2016, In: Rheumatology. 55, 5, p. 918-927 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Increased plasma levels of IL-6 in bacteremic periodontis patients after scaling

    Forner, L., Nielsen, Claus Henrik, Bendtzen, K., Larsen, Tove & Holmstrup, Palle, 1 Oct 2006, In: Journal of Clinical Periodontology. 33, 10, p. 724-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Inflammatory functional iron deficiency common in myelofibrosis, contributes to anaemia and impairs quality of life. From the Nordic MPN study Group

    Birgegard, G., Samuelsson, J., Ahlstrand, E., Ejerblad, E., Enevold, C., Ghanima, W., Hasselbalch, Hans Carl, Nielsen, Claus Henrik, Knutsen, H., Pedersen, Ole Birger Vesterager, Sørensen, A. & Andreasson, B., 2019, In: European Journal of Haematology. 102, 3, p. 235-240

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Influence of Insulin Receptor Single Nucleotide Polymorphisms on Glycaemic Control and Formation of Anti-Insulin Antibodies in Diabetes Mellitus

    Massarenti, Laura, Aniol-Nielsen, C., Enevold, C., Toft-Hansen, H. & Nielsen, Claus Henrik, 2022, In: International Journal of Molecular Sciences. 23, 12, 13 p., 6481.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Influence of Phthalates on in vitro Innate and Adaptive Immune Responses

    Hansen, J. F., Nielsen, Claus Henrik, Brorson, M. M., Frederiksen, H., Hartoft-Nielsen, M., Rasmussen, Å. K., Bendtzen, K. & Feldt-Rasmussen, Ulla, 2015, In: P L o S One. 10, 6, 13 p., e0131168.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Influence of complement on neutrophil extracellular trap release induced by bacteria

    Palmer, L. J., Damgaard, Christian, Holmstrup, Palle & Nielsen, Claus Henrik, Feb 2016, In: Journal of Periodontal Research. 51, 1, p. 70-76 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Interactions of opsonized immune complexes with whole blood cells: binding to erythrocytes restricts complex uptake by leucocyte populations

    Nielsen, Claus Henrik, Svehag, S. E., Marquart, Hanne Vibeke Hansen & Leslie, R. G., 1 Aug 1994, In: Scandinavian Journal of Immunology. 40, 2, p. 228-36 9 p.

    Research output: Contribution to journal › Journal article › Research

  30. Published

    Interferon alpha-2 treatment reduces circulating neutrophil extracellular trap levels in myeloproliferative neoplasms

    Massarenti, Laura, Knudsen, T. A., Enevold, Christian, Skov, V., Kjær, L., Larsen, M. K., Larsen, T. S., Hansen, D. L., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, 2023, In: British Journal of Haematology. 202, 2, p. 318-327 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Interferon-beta increases systemic BAFF levels in multiple sclerosis without increasing autoantibody production

    Hedegaard, C. J., Sellebjerg, Finn Thorup, Krakauer, M., Hesse, D., Bendtzen, K. & Nielsen, Claus Henrik, 1 May 2011, In: Multiple Sclerosis. 17, 5, p. 567-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Interleukin-6-receptor polymorphisms rs12083537, rs2228145, and rs4329505 as predictors of response to tocilizumab in rheumatoid arthritis

    Enevold, C., Baslund, B., Linde, L., Josephsen, N. L., Tarp, U., Lindegaard, H., Jacobsen, Søren & Nielsen, Claus Henrik, Aug 2014, In: Pharmacogenetics and Genomics. 24, 8, p. 401-405 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  33. Published

    Komorbiditet ved marginal parodontitis: To sider af samme sag?

    Holmstrup, Palle, Damgaard, Christian, Olsen, I., Klinge, B., Flyvbjerg, A., Nielsen, Claus Henrik & Hansen, Peter Riis, 2017, In: Tandlaegebladet. 121, 1, p. 52-61

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Linkage Between Periodontal Disease and Rheumatoid Arthritis

    Holmstrup, Palle & Nielsen, Claus Henrik, Jan 2016, Oral Infections and General Health: From Molecule to Chairside. Pedersen, A. M. L. (ed.). 1 ed. Heidelberg: Springer, p. 45-51 6 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  35. Published

    Markers of neutrophil chemotaxis for identification of blood stream infections in children with acute lymphoblastic leukemia undergoing induction treatment

    Weischendorff, S., De Pietri, S., Rathe, M., Frandsen, T. L., Hasle, H., Nielsen, Claus Henrik, Moser, Claus Ernst & Muller, Klaus, 2023, In: European Journal of Haematology. 110, 6, p. 762-771

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Methotrexate induces poly(ADP-ribose) polymerase-dependent, caspase 3-independent apoptosis in subsets of proliferating CD4+ T cells

    Nielsen, Claus Henrik, Albertsen, L., Bendtzen, K. & Baslund, B., 1 May 2007, In: Clinical and Experimental Immunology. 148, 2, p. 288-95 8 p.

    Research output: Contribution to journal › Journal article › Research

  37. Published

    Methylprednisolone prevents tumour necrosis factor-alpha-dependent multinucleated giant cell formation

    Maltesen, H. R., Nielsen, Claus Henrik, Dalbøge, C. S. & Baslund, B., 1 Nov 2010, In: Rheumatology. 49, 11, p. 2037-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Microparticles from patients with systemic lupus erythematosus induce production of reactive oxygen species and degranulation of polymorphonuclear leukocytes

    Winberg, L. K., Jacobsen, Søren & Nielsen, Claus Henrik, 17 Oct 2017, In: Arthritis Research & Therapy. 19, 10 p., 230.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Monozygotic twin pairs discordant for Hashimoto's thyroiditis share a high proportion of thyroid peroxidase autoantibodies to the immunodominant region A. Further evidence for genetic transmission of epitopic "fingerprints"

    Brix, T. H., Hegedüs, L., Gardas, A., Banga, J. P. & Nielsen, Claus Henrik, 1 May 2011, In: Autoimmunity. 44, 3, p. 188-94 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Monozygotic twin pairs discordant for Hashimoto's thyroiditis share a high proportion of thyroid peroxidase autoantibodies to the immunodominant region A. Further evidence for genetic transmission of epitopic “fingerprints”

    Brix, T. H., Hegedüs, L., Gardas, A., Banga, J. P. & Nielsen, Claus Henrik, 1 Oct 2010, In: Autoimmunity.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Mulig sammenhæng mellem marginal parodontitis og iskæmisk hjertesygdom

    Hansen, G. M., Holmstrup, Palle, Tolker-Nielsen, Tim, Køllgaard, T., Nielsen, Claus Henrik, Givskov, Michael & Hansen, Peter Riis, 28 Apr 2014, In: Ugeskrift for Laeger. 176, 18, p. 1752-1754 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Myelin Basic Protein-Induced Production of Tumor Necrosis Factor-α and Interleukin-6, and Presentation of the Immunodominant Peptide MBP85-99 by B Cells from Patients with Relapsing-Remitting Multiple Sclerosis

    Nielsen, Claus Henrik, Börnsen, L., Sellebjerg, Finn Thorup & Brimnes, M. K., Jan 2016, In: PLOS ONE. 11, 1, 13 p., e0146971.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Natural autoantibodies and complement promote the uptake of a self antigen, human thyroglobulin, by B cells and the proliferation of thyroglobulin-reactive CD4(+) T cells in healthy individuals

    Nielsen, Claus Henrik, Leslie, R. G., Jepsen, B. S., Kazatchkine, M. D., Kaveri, S. V. & Fischer, E., 1 Sep 2001, In: European Journal of Immunology. 31, 9, p. 2660-8 9 p.

    Research output: Contribution to journal › Journal article › Research

  44. Published

    Non-Medical Switch from Originator to Biosimilar Infliximab in Patients with Inflammatory Arthritis: Impact on s-Infliximab and Antidrug-Antibodies. Results from the Danish Rheumatologic Biobank and the Danbio Registry

    Glintborg, B., Kringelbach, T. M., Høgdall, E. V. S., Sørensen, I. J., Jensen, D. V., Loft, A. G., Hendricks, O., Hansen, I. M. J., Linauskas, A., Kristensen, S., Lindegaard, H., Nordin, H., Bolstad, N., Warren, D., Gehin, J., Goll, G. L., Grøn, K. L., Eng, G., Enevold, C., Nielsen, C. H. & 2 others, Johansen, Julia Sidenius & Hetland, Merete Lund, 2016, In: Arthritis & Rheumatology. 68, S10, 4 p., 1997.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  45. Published

    Nye behandlinger af Graves' sygdom med fokus på det B-lymfocyt-depleterende antistof rituximab

    Nielsen, Claus Henrik, Fassi, Daniel El & Hegedüs, L., 9 Jun 2008, In: Ugeskrift for Laeger. 170, 24, p. 2131-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Nye behandlingsmuligheder ved primær immun trombocytopeni

    Gudbrandsdottir, S., Frederiksen, H., Birgens, H. S., Nielsen, Claus Henrik, Nielsen, O. J., Stentoft, J. & Hasselbalch, H. C., 24 Jan 2011, In: Ugeskrift for Laeger. 173, 4, p. 271-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Objective and noninvasive biochemical markers in rheumatoid arthritis: where are we and where are we going?

    Bay-Jensen, A. C., Siebuhr, A. S., Damgaard, D., Drobinski, P., Thudium, C., Mortensen, J. & Nielsen, Claus Henrik, 2021, In: Expert Review of Proteomics. 18, 3, p. 159-175 17 p.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Patofysiologien ved primær immun trombocytopeni

    Gudbrandsdottir, S., Frederiksen, H., Birgens, H. S., Nielsen, Claus Henrik, Nielsen, O. J., Stentoft, J. & Hasselbalch, H. C., 24 Jan 2011, In: Ugeskrift for Laeger. 173, 4, p. 274-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Peptidylarginine Deiminase 2 Gene Polymorphisms in Subjects with Periodontitis Predispose to Rheumatoid Arthritis

    Massarenti, Laura, Enevold, C., Damgaard, D., Hansen, Peter Riis, Frisch, M., Ødum, Niels, Jacobsen, Søren & Nielsen, Claus Henrik, 2022, In: International Journal of Molecular Sciences. 23, 17, 10 p., 9536.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Peptidylarginine deiminase-4 gene polymorphisms are associated with systemic lupus erythematosus and lupus nephritis

    Massarenti, Laura, Enevold, C., Damgaard, D., Ødum, Niels, Nielsen, Claus Henrik & Jacobsen, Søren, 2019, In: Scandinavian Journal of Rheumatology. 48, 2, p. 133-140

    Research output: Contribution to journal › Journal article › Research › peer-review

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